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Microcap & Penny Stocks : Tokyo Joe's Cafe / Societe Anonyme/No Pennies -- Ignore unavailable to you. Want to Upgrade?

To: NASDBULL who wrote (22080)	12/4/1998 10:12:00 AM
From: vestor	Respond to of 119973

Be careful on CDCO it is rumor driven just like NETN and look at NETN...

To: NASDBULL who wrote (22080)	12/4/1998 10:18:00 AM
From: Conano	Respond to of 119973

DGIV...if you still own it, check today's price (+.81, 2 3/16 x 2 9/32)...wonder if it's 'for real'... Conan

To: NASDBULL who wrote (22080)	12/4/1998 10:20:00 AM
From: Suntzu	Read Replies (1) \| Respond to of 119973

CALY-Big story by MSNBC today...good chance it will hit TV Urine test shows hidden HIV infection December 3, 1998 07:23 PM (adds interviews, reaction By Maggie Fox, Health and Science Correspondent WASHINGTON, Dec 3 (Reuters) - One out of every 1,000 Americans could be walking around infected with HIV without even knowing it, having passed blood tests, researchers said on Thursday. A new urine test has detected signs of the AIDS virus in the urine of two dozen people who showed no signs of infection in their blood. Now the researchers are working to find out if these people risk getting AIDS and can infect others, or if their bodies have successfully fought off infection. Studies have shown similar findings in groups of people considered at high risk of HIV infection, such as sexually active gay men, but this is the first study to find the urine readings in low-risk people. Dr. Robert Stout, president of Clinical Reference Laboratory (CRL), which did the study, said more than twice as many people tested had signs of virus in their urine as showed it in their blood. "One in a thousand could be walking around and not knowing it -- that's the scary part of it," Stout said in a telephone interview. He said policies on who gets tested, and how, will have to change. "We are going to be testing serum (blood) and urine samples of everyone. I mean literally everyone," he said. "What we are looking at here is challenging the whole idea of HIV infection," he added. "Since we have been studying the blood of people for 15 years, do we really know the full extent of the infection?" The CRL study tested blood and urine samples from more than 50,000 people considered at low risk of HIV infection. It found 19 of them, or about one in 3,000, had evidence of HIV in their blood. That is about the same as the rate as is found in the general population. But when 25,000 of the volunteers who had negative blood tests took a new urine test developed by California-based Calypte Biomedical Corp. CALY , 24 of the samples tested positive for antibodies to HIV in the urine. "So maybe two to three times as many people may be carrying this infection in their urino-genital tract as are serum positive," Stout said. Antibodies are produced by the body to fight infection, and are a good way to see if a virus or bacteria has infected or tried to infect someone. In this case, a specific antibody to HIV known as immunoglobulin A antibody, or IgA, was found. It is produced in the mucous membranes -- which are found in the mouth, nose and throat and also the genital tract. Stout said a big question was whether the body was able to stop the infection in the mucous membranes. Most people are infected through sex, because the mucous membranes are fairly porous and an easy way for a virus to get into the body. Perhaps the infection was stopped cold, or somehow restricted or compartmentalized, in the mucous membranes. If so, the way this was done could be mimicked in a vaccine. Stout's company is now using techniques that look for genetic material from the virus itself to check this. "Could these people in fact be harboring the virus in the genital-urinary tract and passing the virus from that while still not having a systemic infection?" he asked. Howard Urnovitz, chief scientific officer at Calypte, said the findings could explain people who mysteriously die of AIDS without having signs HIV infection, and could shed light on why some people resist infection. "We have known for years that we have people that are in high risk groups that are chronically exposed to the virus and yet never develop a systemic infection," he said. "This is really an opportunity for us to look at these people and see how their immune system has handled the virus." Such a study might offer good candidates for a vaccine, he added. Calypte stock was up more than $1 on the news, at 3 7/8. REUTERS 13m shares out 10m float