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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: Robert K. who wrote (7962)12/7/1998 11:31:00 AM
From: aknahow  Respond to of 17367
 
Bob, not sure what to do with this. Here you take it.

golgi.harvard.edu



To: Robert K. who wrote (7962)12/7/1998 12:53:00 PM
From: aknahow  Read Replies (1) | Respond to of 17367
 
Got my UPS packages. Voted by phone. Easy to do. Can also do it on the internet.



To: Robert K. who wrote (7962)12/7/1998 1:30:00 PM
From: aknahow  Respond to of 17367
 
Robert, you should find of interest. Do search for BPI. Also do search again.

pctvmag.com

. "BPI potently neutralizes LPS of
any chemotype, but p15s and defensins are less active against long-chain (S-type) LPS. In whole blood ex vivo, the
p15s and NP1 are approximately 1000-fold less potent than BPI,"

"Thus, BPI
stands out for its ability to inhibit isolated or bacterial LPS under physiologic conditions."

"Thus, BPI stands out for its ability to inhibit isolated or bacterial LPS under physiologic conditions.
However, p15s and defensins may also contribute to supression of endotoxic signaling by Gram-negative bacteria via
synergistic (with BPI) growth inhibition upon extracellular release of these proteins from PMN during inflammation"