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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?

To: Robert K. who wrote (7999)	12/10/1998 11:49:00 AM
From: Bluegreen	Respond to of 17367

Bob, your question should be how will ER and other clinicians use BPI as soon as it gets approval for ANY indication. Only then will we see whether or not our investment pays off. Only my opinions.

To: Robert K. who wrote (7999)	12/10/1998 10:07:00 PM
From: Bluegreen	Respond to of 17367

>>>>>>''If the early-warning system fails, the infection continues to spread throughout the body,'' explained Beutler in a statement. ''This can result in massive overproduction of (chemical weapons against infection which)... can cause shock.'' ''It will take a while to determine if there are equivalent mutations in the gene'' in humans, Beutler told Reuters Health, but it is ''very likely'' that there are, he said. ''If it is the case that many cases of septic shock are actually attributable to mutations in the gene,'' the finding may lead to the development of a test to identify patients at risk, who could then be treated with prophylactic antibiotics, Beutler explained. Alternatively, drugs could be developed to block the process, preventing shock while the infection is controlled with antibiotics. Currently, Beutler said, ''We can treat gram-negative (bacterial) infections themselves, but we can't treat the shock that results from gram-negative infection.''<<<<<<< You don't have to worry about the failure of the "early warning" system IF you can destroy the bacteria rapidly enough. If only there was a protein molecule to help antibiotics work better! Something that actually poked holes in gram neg. bacteria. Last statement made by Beutler above is ludicrous in my opinion. WE DON'T EVEN COME CLOSE TO TREATING GRAM NEG BACTERIAL INFECTIONS THEMSELVES IN RAPID AND EFFECTIVE MANNER AND SITUATION IS ONLY GETTING WORSE!!! If the bacterial infection was shut down rapid enough there would not be enough sustain LPS presence to cause even the early warning system as described above to be activated. Only my opinions.