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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: Robert K. who wrote (8008)12/11/1998 11:06:00 AM
From: aknahow  Respond to of 17367
 
Bob, looking for that found this. Detailed links to specialized journals.

wkap.nl



To: Robert K. who wrote (8008)12/11/1998 11:14:00 AM
From: aknahow  Read Replies (4) | Respond to of 17367
 
And this:

spin.it

Do not ignore. Scroll to end. Much on sepsis, but you only get to see title of presentations.



To: Robert K. who wrote (8008)12/11/1998 11:20:00 PM
From: aknahow  Respond to of 17367
 
Here is the link to the Journal site. Can you get to one you want? Don't know have not yet tried.

link.springer.de



To: Robert K. who wrote (8008)12/11/1998 11:30:00 PM
From: aknahow  Read Replies (2) | Respond to of 17367
 
PDF Pretty Damn Funny. Found it, but can't read it. Sorry I still don't know how to make it work, even after loading the Adobe Reader.

Go to the prior post where link to Journal is. Then go to 1998 and you will see months listed 12,11,10 etc. issue number is in front. Long explanation because. Well Bob, just because....




European Journal of Pediatrics

ISSN: 0340-6199 (printed version)
ISSN: 1432-1076 (electronic version)

Table of Contents

Abstract Volume 157 Issue 11 (1998) pp 869-880

review: Pathophysiology of meningococcal sepsis in
children

E. D. de Kleijn, J. A. Hazelzet, R. F. Kornelisse, R. de Groot

Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands,
Tel.: +31-10-4636691, Fax: +31-10-4636449

Received: 9 February 1998 / Accepted in revised form: 26 May 1998

Abstract Septic shock with purpura is a syndrome frequently diagnosed in children and
predominantly caused by Neisseria meningitidis. Despite improvements in management and
therapy the mortality and morbidity in these patients are still high. During the last few years
much effort has been put into understanding of the systemic host response during this acute
infectious disease. This host response can be divided into the process of recognition of
endotoxin, the cascade of pro- and counter inflammatory mediators, the endothelial damage
resulting in capillary leakage and inappropriate vascular tone, and the procoagulant state.

Conclusion This paper reviews the recent insights in the pathophysiology of the host
response and their possible consequences for novel therapies in meningococcal sepsis.

Key words Meningococcal infection · Sepsis · Children · Pathophysiology · Treatment

Article in PDF format (297 KB)

Online publication: October 27, 1998
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© Springer-Verlag Berlin Heidelberg 1998