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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?


To: bob zagorin who wrote (26910)12/15/1998 2:04:00 PM
From: Henry Niman  Read Replies (1) | Respond to of 32384
 
LGND's approach to asthma has been briefly described:
Message 3416750
LGND targets STATs that control IL-4 expression. IL-4 is one of the first cytokines released by mast cells.
The AXPH-Bayer tryptase inhibitor targets a serine protease which is also released by mast cells.
LGND targets one of the involved proteins (IL-4) by shutting down its production, while AXPH targets another protein, by inhibiting the enzymatic activity.

To get a feel for other biotechs targeting asthma, go to biocognizance.com and search for asthma. Although the site is far from complete, it will show some biotechs that mention asthma in their background paragraph.

PS If the bouncing letters are distracting, or take too long to come in, just hit "stop" on your browser (which will stop the letters in their tracks), and then do the asthma search.



To: bob zagorin who wrote (26910)12/18/1998 6:50:00 AM
From: Henry Niman  Read Replies (1) | Respond to of 32384
 
bob, CNBC just announced that they would be discussing a new approach to asthma and this morning the WSJ has an extensive article on programs targeting IL-4, IL-5, and IL-13.
LGND's program targets IL-4.
I have started a thread at:
biocognizance.com