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Strategies & Market Trends : Trader J's Inner Circle -- Ignore unavailable to you. Want to Upgrade?


To: steve brooks who wrote (2376)12/21/1998 10:50:00 AM
From: BANCHEE  Read Replies (1) | Respond to of 56535
 
Steve
Will look for it but
I don't think it matters
anymore. We are on the move.
towards Jan ern.
Banchee



To: steve brooks who wrote (2376)12/21/1998 11:00:00 AM
From: BANCHEE  Read Replies (1) | Respond to of 56535
 
Trader J
Market is hot.
Buying CNSI with great news and conference
call at 12 (1-888-243-0813)
Stock dip after morning sell off will buy now on dip.
This could be a day trade or short term trade.

Monday December 21, 7:55 am Eastern Time

Company Press Release

SOURCE: Cambridge NeuroScience, Inc.

Cambridge NeuroScience and Bayer
to Collaborate in the Development of GGF2 For
Neurodegenerative Diseases

-- Bayer to Pay Up to $26 Million Plus Royalties --

CAMBRIDGE, Mass., Dec. 21 /PRNewswire/ -- Cambridge NeuroScience, Inc. (Nasdaq:
CNSI - news) and Bayer today announced an agreement worth up to $26 million plus royalties to
develop Cambridge NeuroScience's recombinant Glial Growth Factor 2 (GGF2), for the
treatment of neurodegenerative diseases such as Multiple Sclerosis (MS).

(Photo: newscom.com

Under terms of the agreement, Bayer will be responsible for all development costs, including
reimbursement of Cambridge NeuroScience's research costs for GGF2 and will receive exclusive
worldwide manufacturing and marketing rights to the compound. In exchange, Cambridge
NeuroScience may receive up to $26 million in cash and milestone payments, as well as royalties
on sales of GGF2 products.

''Cambridge NeuroScience and its academic collaborators have generated impressive data
demonstrating the unique mechanism by which GGF2 stimulates the remyelination of nerve cells,''
said David Lowe, Ph.D., head of CNS research at Bayer. ''The companies have worked together
in developing a manufacturing process for the molecule.''

''We are pleased to be joining forces with Bayer, whose proven capabilities should accelerate the
development of GGF2,'' said Harry Wilcox, President and Chief Executive Officer of Cambridge
NeuroScience. ''The two teams have worked together in developing a manufacturing process for
the molecule, and in the last year have begun production of GGF2 in anticipation of initiating
clinical trials. The partnering of GGF2 is in line with our corporate strategy of focusing our internal
efforts on our small molecule and ion-channel blocker programs.''

GGF2, a member of the neuregulin family of growth factors, is known to stimulate the growth and
differentiation of glial cells, the support cells of the nervous system. These glial cells form the myelin
sheath that insulates nerve cells and is essential for their survival and proper functioning. In
demyelinating diseases such as multiple sclerosis, the myelin sheath is damaged or lost, leading to
the degeneration of the nerve cells. Experiments in animal models have demonstrated that GGF2
can stimulate the cell growth necessary to protect and potentially regenerate the damaged myelin
sheath.

Recent data on GGF2 in multiple sclerosis was published in the August 18, 1998 issue of
Proceedings of the National Academy of Sciences. The study, conducted by CNSI in conjunction
with Drs. Cedric Raine and Barbara Cannella at Albert Einstein College of Medicine in New
York, demonstrated that treatment in an animal model of MS with recombinant human GGF2
leads to delayed onset and decreased disease severity, as well as a statistically significant reduction
in relapse rate.

Cambridge NeuroScience, Inc. is a neuroscience company engaged in the discovery and
development of proprietary pharmaceuticals focusing on nerve cell survival. The Company is
developing products to treat stroke and chronic neurodegenerative disorders such as multiple
sclerosis, peripheral neuropathies and other degenerative diseases.

Bayer Corporation is a research-based company with major businesses in healthcare and life
sciences, chemicals and imaging technologies. The company had 1997 sales of $9 billion and
employs 24,000 people. Bayer Corporation is investing approximately $9 billion in capital
expenditures and research and development in the U.S. operations from 1995 through the year
2000. Bayer Corporation, with headquarters in Pittsburgh, is a member of the worldwide Bayer
group, a $32.4 billion pharmaceutical and chemical company based in Leverkusen, Germany.

This press release may contain forward-looking statements based on the current expectations of
management. There are certain important factors that could cause results to differ from those
anticipated by the statements made above, including, but not limited to, the results of the ongoing
pre-clinical studies of GGF2 and the acceptance by regulatory authorities of the Company's
pre-clinical data as a basis for IND approval.

SOURCE: Cambridge NeuroScience, Inc.

More Quotes and News:
Cambridge NeuroScience Inc (Nasdaq:CNSI - news)
Related News Categories: biotech, medical/pharmaceutical