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Biotech / Medical : Vion (formerly Oncorx) interesting play on Gene Therapy -- Ignore unavailable to you. Want to Upgrade?


To: Michael Cash who wrote (121)12/30/1998 11:41:00 AM
From: scaram(o)uche  Read Replies (1) | Respond to of 370
 
The "flesh-eater" is Gram-positive (Salmonella is Gram-negative), so I don't know if it would selectively home to a tumor. Lots of other reasons that you wouldn't want to do this, and that the FDA would kick you in the butt for even thinking about it. The question, however, is rational when framed in the original irrational VION frame.

The trend is clearly to use an innocuous bug to deliver something that is tumor-selective, a prodrug for example.

See the abtract linked from my previous post.