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Biotech / Medical : wla(warner lambert) -- Ignore unavailable to you. Want to Upgrade?


To: Greg Jenkins who wrote (436)1/20/1999 11:04:00 PM
From: Greg Jenkins  Read Replies (1) | Respond to of 942
 
Here are the comments from individual investor magazine website. iionline.com.

There are 4 comments since November 18. I will post each separately.

WARNER-LAMBERT

BUSINESS: Pharmaceuticals maker

WHY WE LIKE IT: A new emphasis on drug development has delivered two blockbusters and will add to the company's steady slow-growth business.

FINANCIAL ANALYSIS: Nine-month revenue was up 25%, boosted by a doubling of sales of cholesterol drug Lipitor. Earnings grew 42%.

OUTLOOK FOR 1999: New antidepressant should help boost earnings 32%, to $1.92 a share.

It's not just the relief of Rolaids, which many investors surely craved this past summer, that has made their maker, Warner-Lambert, a Wall Street darling. Under the direction of chairman and CEO Melvin Goodes for the past 10 years, the maker of such well-known consumer products as Listerine, Chiclets, Trident, and Certs has been beefing up its pharmaceutical research division, and that has spelled p-r-o-f-i-t-s. Two new Warner-Lambert drugs—Lipitor for cholesterol reduction, and Rezulin for diabetes—are on a roll.

The entire pharmaceutical industry has been doing well, but Warner-Lambert, once a laggard, has been the fastest-growing U.S. drug firm. The company has been developing drugs since 1881, mostly over-the-counter cold remedies and personal-hygiene products. In 1970, with the acquisition of Parke, Davis & Co., it got more involved in prescription pharmaceuticals. Shuttling a drug though the Food and Drug Administration approval process can take as long as 12 years, but Warner-Lambert is finding the large payoff is worth it. Earnings have accelerated, from $740 million on $7 billion in sales in 1995 to $870 million on $8.2 billion in sales in 1997, but the biggest jump came in 1998. In the third quarter, earnings increased 46%, to $0.35 a share, beating expectations by a penny.

Much of the recent growth can be attributed to Warner-Lambert's stunning success with Lipitor, which was approved in December 1996. Before Pfizer's Viagra hit the market in April, Lipitor was considered the best new drug launch ever. Rezulin also has been a winner for Warner-Lambert, and should add about $740 million in sales in 1998. Other medications currently on the market are Neurontin, which is for epilepsy, and Accupril, which treats hypertension and was recently found to greatly reduce the reoccurrence of heart disease in patients who had bypass surgery. But Lipitor has been the blockbuster. According to CIBC Oppenheimer analyst Mara Goldstein, "This drug has taken its market by storm, leaping to a 42% share without one print ad to consumers." Thanks to Lipitor, Warner-Lambert was able to add $2 billion in revenue in 1998. In one year it effectively doubled the business of Warner-Lambert's pharmaceutical division, which now accounts for more than half of company revenue. "There's some concern that Lipitor could have been a flash in the pan," says Goldstein, "but Lipitor has a long way to go, and the company has good marketing skills."

Goodes says he wants the company to depend on Lipitor for no more than 20% of total revenue, which means producing another blockbuster drug is high among his priorities. One in the pipeline is Celexa, a Prozac-like antidepressant that is nearing launch, whose 1998 sales are projected at $50 million, but could reach $500 million in 2001, according to Goldstein.

Although the stock, at a recent $74, trades at high multiples—51 times 1998 estimates of $1.46 a share and 39 times 1999 estimates of $1.92—the valuation seems warranted given forecasted growth of 32% in 1999, reliable earnings from its well-known consumer products, and management's record of producing a high return on equity. Considering its projected growth rate, analyst David F. Saks at Gruntal & Co. thinks Warner-Lambert is the best value among large drug manufacturers. He thinks shares could rise 33%, to $98, in the next 12 months.

—Dave Lindorf



To: Greg Jenkins who wrote (436)1/20/1999 11:06:00 PM
From: Greg Jenkins  Respond to of 942
 
12/9/98 Warner Lambert: Concern Regarding Diabetes Drug Rezulin

The Los Angeles Times reported that 33 deaths are being blamed on liver damage in patients taking Warner Lambert's (NYSE:WLA) blockbuster diabetes drug Rezulin. This same paper reported earlier that an FDA officer assigned to evaluate Rezulin, Dr. John L. Gueriguian, recommended rejecting the drug after documenting its possible danger to the liver. After voicing his concerns, it is reported that Dr. Gueriguian was summarily removed from the review in late 1996 by senior FDA officials. Further reports detail that at least one government researcher who was to evaluate an impartial study on Rezulin may have also been employed by the company, thereby generating a conflict of interest. The company has yet to make a formal statement regarding these events.

Rezulin was given "fast track" review, and was approved in December 1996. The product has remained on the US market, despite past concerns about toxicity because it is the only product that re-sensitizes the body to insulin and helps reduce diabetes patients blood sugar enough so that fewer daily injections of insulin are needed. Rezulin sales were up 32% this past quarter to $181 million helping the company boost its profitability 49% to $296 million. It has been estimated that Rezulin will generate $740 million in revenue for Warner Lambert in FY 1998 and $1 billion, or roughly 8.5% for total estimated sales of $11.7 billion in FY 1999. Rezulin in conjunction with Lipitor (for cholesterol reduction) is among the company's most crucial products in the pharmaceutical giant's pipeline. Lipitor and Rezulin revenues by FY 2002 have been estimated to be in the range of $7 billion.

It is possible that the FDA may review reports of Rezulin's liver toxicity in greater detail. There is also a possibility that the drug could be recalled in the interim. Based upon conversations with individuals at the company (who declined direct quotation), however, we are not expecting any serious fallout from this wave of reports.

We like Warner Lambert because of its diversification in both pharmaceuticals and confectionery products (roughly a 44% and 56% split respectively). We believe that the company's overall estimated earnings growth of just over 30% ($1.48E in FY 1998, and $1.95E in FY 1999), its history of developing highly regarded pharmaceuticals and consumer products from an extensive R&D pipeline, and future opportunities for growth should far outweigh the short-term negative impact that this news is expected to generate. We would advocating purchasing shares on weakness, and upon the release of a formal statement by the company detailing their accounts of this week's news.

We acknowledge that the company trades at multiples considered "rich" by Wall Street standards (roughly 39x FY 1999 estimates, 19.6x book value, over 40x cash flow, and over 6x revenues). However, among the leading pharmaceutical companies we believe that Warner Lambert's pipeline offers the fastest growth, and potentially the richest reward to shareholders.

Analyst: Glenn Curtis

(Updated 12/7/98 with WLA trading at $75.25)
Recommended 11/16/98 at $73.63



To: Greg Jenkins who wrote (436)1/20/1999 11:09:00 PM
From: Greg Jenkins  Read Replies (1) | Respond to of 942
 
12/15/98 Warner-Lambert Responds to Rezulin controversy

Warner Lambert responded to an article first circulated in the LA Times regarding 33 deaths, reportedly caused by liver damage in patients taking the drug Rezulin (for Type 2 diabetes). The company stated that it had always been forthcoming regarding safety and efficacy concerns with the FDA. Moreover the company feels that the article unfairly ignored the "significant" benefits the drug provides.

The company went on to say that the risk-reward ratio when consuming Rezulin should be taken into account. Of the hundreds of thousands currently taking the product, the company has claimed that incidences have been relatively few and far between. To date over 1.4 million patients have begun Rezulin therapy in the U.S. alone. Warner Lambert has stated that they intend to monitor adverse events through increased surveillance, and that they will quickly report any adverse findings to the FDA. Discussions with the company have led us to believe that the company has no immediate intention of recalling Rezulin.

Also, 10 different insiders have recently exercised over 350,000 options (including 162,000 by officer, Anthony Wild) and sold the underlying stock in the company in late November. According to the company these options had to be exercised, or they would have been lost by year-end. No reason was given however for the sale of the securities which followed the exercise. While insiders continue to own a significant amount of stock, and options the transactions were sizeable and should not be ignored.

Analyst: Glenn S. Curtis

(Updated on 12/15/98 with WLA trading at $73.63) Recommended 11/16/98 at $73.63



To: Greg Jenkins who wrote (436)1/20/1999 11:10:00 PM
From: Greg Jenkins  Read Replies (1) | Respond to of 942
 
1/20/99 Warner Lambert is Fine Despite Rezulin Controversy: Buy

On January 15, Warner Lambert (NYSE: WLA) said that Rezulin, the company's FDA approved drug for type 2 diabetics will be reviewed by an FDA advisory committee on March 26, 1999.

There has been concern that Rezulin has led to patient deaths. It has been known for quite some time however that use of the product could lead to toxicity of the liver, and abnormal liver function. It has been the company's position, and thus far the FDA's position that the product has been more helpful than harmful to patients, and that the product should remain on the market. The company hopes that this review will help alleviate public concern. We tend to agree and believe this "airing" may clear the air much as was the case when Elli Lilly's (NYSE: LLY) Prozac was reviewed and a clean bill of health was issued several years ago.

Warner Lambert's spokesman, Jack Howarth recently said, "Warner Lambert is not concerned at all with a review of Rezulin. There are thousands of individuals who are more than happy with this product, and the fact that it has saved their lives." Howarth went on to say that he did not believe that this review of safety and efficacy data would yield any adverse consequences. Howarth said that it "is not uncommon for a controversial product, as Rezulin has certainly been, to be reviewed. In the end this could help us."

The company's sentiments were essentially echoed by CIBC Oppenheimer analyst Steven G. Gerber, who rates the stock a "buy". Gerber said "that the FDA review should have no impact on the company. Certainly we not believe that the product would at all be shelved or recalled". Gerber believes that the company will earn $0.40 per share in the fourth quarter ending December 31, 1998, and $1.48 per share for FY 1998. In FY 1999 his estimates are $1.95 per share. His price target is $80.00 per share.

Rezulin is taken by roughly 1.4 million Americans. In the third quarter alone Rezulin generated $181 million in revenue for the company despite "public concerns" about the safety and efficacy of the product. In FY 1999 it is estimated to generate $1 billion in revenue for the company. This is equivalent to about 7.8% of total estimated revenue of just over $12 billion in FY 1999.

Analyst: Glenn S. Curtis

Updated January 20, 1999 with WLA trading at $65.81.

Recommended 11/16/98 at $73.63