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Biotech / Medical : GLGC Gene Logic -- Ignore unavailable to you. Want to Upgrade?


To: Steve Lokness who wrote (30)1/25/1999 5:53:00 PM
From: Mike McFarland  Read Replies (1) | Respond to of 360
 
Thanks...the puzzle is starting to come
together for me. I'll go back and read
through the thread quickly to see what
I find...but for now, another question:-)

I know GLGC got a lot of tissue samples
from Oncormed...but where are the compounds
for screening coming from--do biotech
companies subscribe to a service where
a van from, say, Pharmacopia pulls up once
a months with thousands of new molecules
on which GLGC runs their assays?

(did I even phrase that right!?)

Also, does GLGC have a database of useful
polymorphisms--apparently there are something
like 5000 publicly-known SNPs--but I dont even
know how many of those are outside of the genes
which are actually expressed.

I heard something about Iceland selling their
genetic data for this reason, so I am guessing
mutation data is valuable--the vcall recording
did get one thing to sink into my head, that
glgc beleives it can help stratify the composition
of people in trials if leads do go clinical...
and for that you have to know the SNPs, right?

How all this happens from the flow-through-chip,
to screening, to clinical trials is not at all
obvious to me yet however.

--Mike