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Biotech / Medical : Human Genome Sciences, Inc. (HGSI) -- Ignore unavailable to you. Want to Upgrade?


To: Steven Rachbach who wrote (247)2/11/1999 10:04:00 AM
From: Steven Rachbach  Respond to of 1127
 
Human Genome Sciences Reports 1998 Financial Results ROCKVILLE, Md., Feb. 11 /PRNewswire/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI) today reported revenues of $29.6 million and a net loss of $23.2 million, or $1.03 per share, for the year ended December 31, 1998. This compares to revenues of $25.6 million and a net loss of $21.4 million, or $0.99 per share, for the year ended December 31, 1997. The difference in revenues is primarily attributable to final payments received by HGSI under its collaboration with Pioneer Hi-Bred, and the recognition of revenues relating to the agreement with Transgene, S.A., both in 1998. Cash and short-term investments totaled $188.5 million, including $6.7 million of restricted cash, at December 31, 1998, compared to $211.8 million, including $6.6 million of restricted cash, at December 31, 1997. For the fourth quarter ended December 31, 1998, HGSI recorded revenues of $2.4 million and a net loss of $12.5 million, or $0.55 per share, compared to revenues of $3.0 million and a net loss of $8.5 million, or $0.38 per share, during the fourth quarter of 1997. The increase in net loss for the quarter compared to the fourth quarter of 1997 was primarily attributable to the recognition of losses from the Company's joint venture, Vascular Genetics Inc., increased pre-clinical and clinical research and development expenses and a decrease in revenue recognition under the Company's collaboration with Pharmacia & Upjohn, Inc. At the current time, HGSI has filed patent applications on more than 2,800 novel human genes. The number of genes and proteins for which patent applications have published under the auspices of the Patent Cooperation Treaty is now over 1,100. The number of genes now covered by U.S. notices of patent allowance is 78, of which 56 are covered by issued patents. All of these patents and patent applications cover inventions based on full-length sequences of human genes with proposed medical applications. "The financial results for the quarter and full year are in line with management's expectations," said Steven C. Mayer, Senior Vice President and Chief Financial Officer. "HGSI achieved several milestones in 1998 that mark the Company's ongoing transition to a fully integrated pharmaceutical company. Among these are the initiation of three human clinical study programs for two novel human proteins, Myeloid Progenitor Inhibitory Factor-1 and Keratinocyte Growth Factor-2. Furthermore, our joint venture company, Vascular Genetics Inc., initiated a human clinical study program with a gene therapy product based on Vascular Endothelial Growth Factor-2. To further leverage the gene therapy rights of the genes discovered by HGSI, the Company formed a new collaboration, with Transgene S.A. for the development and marketing of gene therapy products. In addition, construction of the Process Development and Manufacturing facility is nearing completion. It will enable HGSI to produce therapeutic proteins under cGMP requirements for clinical trials and possibly for commercial launch." "An important component of the Company's strength is HGSI's financial position," said Mr. Mayer. "The product development agreements into which the Company has entered have provided substantial funding to date and, potentially, will provide a long-term revenue stream from the sale of our partners' products. This has allowed the Company to select carefully which therapeutic proteins and genes to develop as HGSI's proprietary pharmaceutical products, while maintaining a strong cash position." Human Genome Sciences is a company whose mission is to develop products to predict, prevent, detect, treat and cure disease based on its leadership in the discovery and understanding of human and microbial genes. HGS and Human Genome Sciences are registered trademarks of Human Genome Sciences, Inc. For additional information on Human Genome Sciences, Inc., visit the company's web site at hgsi.com. Copies of press releases are also available by fax 24 hours a day at no charge by calling 800-758-5804, ext. 121115. Any statements released by Human Genome Sciences, Inc. that are forward looking are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Readers are cautioned that forward looking statements involve risks and uncertainties which may affect the Company's business prospects and performance. These include economic, competitive, governmental, technological and other factors discussed in the Company's filings with the Securities and Exchange Commission on forms 10-K and 10-Q. HUMAN GENOME SCIENCES, INC. SELECTED FINANCIAL DATA Three Months Ended Year Ended 12/31/98 12/31/97 12/31/98 12/31/97 (In thousands, except share and per share data) Statement of Operations Data: Revenue-research and development Collaborative contracts $2,392 $2,966 $29,598 $25,605 Costs and expenses: Research and development: Direct expenditures 12,317 11,310 47,006 39,893 Payments under research services agreement -0- 106 -0- 6,247 General and administrative 3,834 3,195 14,370 11,113 Total costs and expenses 16,151 14,611 61,376 57,253 Income (loss) from operations (13,759) (11,645) (31,778) (31,648) Net Interest income 2,838 3,158 11,047 10,500 Equity in income (loss) of joint venture (1,624) -0- (2,226) -0- Income (loss) before taxes (12,545) (8,487) (22,957) (21,148) Provision for income taxes -0- -0- 225 245 Net income (loss) $(12,545) $(8,487) $(23,182) $(21,393) Net income (loss) per share $(0.55) $(0.38) $(1.03) $(0.99) Weighted average number of shares 22,605,748 22,308,195 22,434,131 21,525,283 December 31, 1998 December 31, 1997 Balance Sheet Data: Cash, cash equivalents and short-term investments(a) $188,516 $211,794 Total assets 244,247 236,232 Long-term debt, net of current portion 1,780 2,224 Total stockholders' equity 208,848 223,254 (a) Includes $ 6,749 and $6,582 in restricted cash at December 31, 1998 and December 31, 1997, respectively. SOURCE Human Genome Sciences, Inc. CO: Human Genome Sciences, Inc. ST: Maryland IN: MTC SU: ERN 02/11/99 06:50 EST prnewswire.com