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To: Anthony Wong who wrote (1427)2/14/1999 2:13:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 1722
 
Immunex Shares Fall as Pace of New Enbrel Prescriptions Slows

Bloomberg News
February 13, 1999, 11:15 a.m. ET

Immunex Shares Fall as Pace of New Enbrel Prescriptions Slows

Washington, Feb. 13 (Bloomberg) -- Immunex Corp. shares slid
15 percent in the first two weeks of February, as investors
realize it will take some time for the company's hot new
arthritis drug Enbrel to reach its potential, analysts said.

Shares in Seattle-based Immunex fell 2 3/8 to 136 5/8
Friday.

Enthusiasm for Enbrel caused shares in Immunex to more than
triple since October, peaking at 163 1/8 Feb. 1. The rise was
driven by the company's reports that Enbrel sales had beaten
expectations, and that the company's drug was the subject of a
favorable study in an influential medical journal.

Shares began their slide after officials, while reporting
the company's first-ever profit for the fourth quarter, said
Immunex will likely lose money over the next two quarters as it
spends in order to further establish Enbrel on the market.
Immunex fell 6 percent on the news. The stock's continued slide
has been fueled by a dip in the growth of new prescriptions for
Enbrel, according to weekly numbers released on Monday.

''The new prescriptions were down 5 percent over last week,
and that can certainly have an effect,'' said Michael King, a
biotechnology analyst with BancBoston Robertson Stephens, who has
a ''long term attractive'' rating on Immunex.

Lull in New Prescriptions

For the week ending Jan. 22, there were 2,169 new
prescriptions for the drug, down from the 2,286 new prescriptions
doctors wrote for Enbrel the during previous week, according to
IMS Health, a firm that tracks prescription and sales trends for
drugs.

Analysts though said that a lull in new prescriptions is a
normal event during the course of new drug launch. Initially,
demand for Enbrel surprised investors, and sales for the fourth -
quarter beat analysts expectations by more than a $1 million.

''We shouldn't make too much out of this. New drugs don't go
straight up, and nothing goes in a straight line,'' said
BancAmerica's King.

Immunex shares rose 13 percent on Wednesday and Thursday,
before falling again yesterday.

The drop in Immunex is due in part to the fact that the
company's stock had more than tripled since October, driven by
high hopes for Enbrel, analysts said.

''The stock was just priced too high,'' said Meirav Chovav,
an analyst with Salomon Smith Barney. ''Enbrel is a very good
drug, and Immunex is a very good company.''

New Class of Therapies

Salomon's Chovav cut her rating on the stock to a
''neutral'' on Feb. 2, after the stock's price rose too high, she
said. Her 12-month target price is 140.

Immunex, which is majority-owned by drugmaker American Home
Products Corp., reported fourth-quarter net income of $11.04
million, or 26 cents a share after a loss of 4.57 million, or 12
cents, a year earlier. Enbrel had 12.7 million in sales in the
fourth quarter.

The drug is among the first in a new class of therapies that
combat diseases like rheumatoid arthritis by blocking a naturally
occurring protein called Tumor Necrosis Factor, which plays a key
role in inflammation.

Centocor Inc. has applied for FDA clearance to sell its
Remicade drug to treat rheumatoid arthritis. Remicade, which
is already approved to treat a severe bowel disorder called
Crohn's disease, targets the TNF protein differently.

Immunex's chief executive officer has said he expects the
company to record a full-year profit at the end of 1999.

''There is nothing fundamentally wrong,'' Chovav said. ''The
company is doing great -- the stock just got ahead of itself.''

--Kristin Reed in Washington (202) 624-1858/ mfr