SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: BigKNY3 who wrote (7033)2/18/1999 9:00:00 AM
From: Anthony Wong  Respond to of 9523
 
BBC: 'Stop Viagra mail shots'
Mail shots are used to advertise Viagra
Wednesday, February 17, 1999 Published at 19:05 GMT

The government has been urged to outlaw attempts to
market Viagra by unsolicited mail shots.

The practice has been condemned for exploiting the
embarrassment of impotent men, and encouraging them
not to seek expert help when they could be suffering
from serious medical conditions.

Calling on Health Secretary Frank Dobson to intervene,
Tory MP Roger Gale said Viagra was a therapeutic drug
"and not a recreational toy".

Mr Gale, MP for Thanet North, said a mail shot
advertising packets of 30 Viagra tablets for £450 had
been sent to a constituent, who wanted to remain
anonymous, in Herne Bay, Kent.

The literature was attributed to Swiss company Medica
International Pharmaceuticals, but the company was
untraceable, and the package was posted in Liverpool.

The documents prominently use the name of Pfizer, the
manufacturers of Viagra, without authority.

They say: "If you use it for special occasions it is
guaranteed to provide you and your partner with an
enriching and fulfilling experience that will enhance a
loving relationship."

They go on: "The prescription drugs we supply are
specialist medicines which can prove difficult or
embarrassing to obtain via your own medical
practitioner."

They explain under what conditions Viagra should and
should not be taken.

Fast buck

Pfizer, which manufactures
Viagra, said it is doing
everything it can to stamp
out mail shot marketing of
the drug.

A spokesman said: "What
the publicity surrounding
Viagra has done is to
encourage a lot of people
who are out to make a fast
buck to try and market it
wherever they can through
junk mail or mail shots.

"We want to make absolutely clear that we operate as
an ethical pharmaceutical company and have nothing to
do with these other companies, do not sanction what
they are doing and do all we can to prevent any illegal
trading like this."

He said the unauthorised use of trademarks could be a
criminal offence.

He also warned that erectile dysfunction in eight out of
10 cases was caused by another medical condition,
which would remain undisclosed if people did not go to a
doctor and got Viagra through a mail-shot.

People who might be too embarrassed to go to a doctor
might respond to a mail shot which, like this one,
promised "maximum confidentiality" with the goods
packed under plain cover, he added.

"We want to protect our good reputation and the
reputation of this brand, and make sure it is used only
for its intended purposes. If you are a normal, healthy
young male, you are wasting your money."

news.bbc.co.uk



To: BigKNY3 who wrote (7033)2/18/1999 12:04:00 PM
From: Anthony Wong  Respond to of 9523
 
Bob Dole in ad for impotency drug

Copyright © 1999 Nando Media
Copyright © 1999 Agence France-Press

WASHINGTON (February 17, 1999 10:03 p.m. EST nandotimes.com) - Bob Dole, the former Senate leader who ran against President Clinton in 1996, was featured this week in a full page newspaper ad by Pfizer, the manufacturer of the wonder drug
Viagra.

"It may take a little courage to ask your doctor about erectile dysfunction (ED)," says the caption. "But everything worthwhile usually does."

Apparently his wife, Elizabeth, agrees.

Last May, after Dole went public about his prostate cancer and his participation in Viagra trials, "Liddy" Dole told a press conference she thought it was a "great drug."

Bob Dole, 75, says in the Pfizer ad that he is speaking candidly about his experience "in the hopes that men with ED will get proper treatment for a condition that affects millions of men and their partners."

But there may be other incentives from the huge pharmaceutical company.

A Pfizer spokeswoman would not say how much Dole was being paid for the ad, which does not specifically mention Viagra, but acknowledged that Dole "is being reimbursed for his time."

Dole, who is also featured in a television ad, has said he is doing the campaign as a community service.

Viagra is sold as a pill that must be taken a full 60 minutes before sexual relations to help stimulate an erection. Its sales have sky rocketed since the Food and Drug Administration approved Viagra last March.

www2.nando.net



To: BigKNY3 who wrote (7033)2/18/1999 12:09:00 PM
From: Anthony Wong  Read Replies (2) | Respond to of 9523
 
Womanizing Viagra, What started as an impotence drug for men is getting good reviews from women who want heightened feeling

by Jenice M. Armstrong
February 18, 1999
Philadelphia Daily News
Daily News Staff Writer

After years of searching, Elizabeth Belt finally met the man of her
dreams. Not only was he handsome and kind, but he also got along
well with her three children. Theirs was a storybook romance.

Except for one thing: Belt couldn't feel anything sexually. At first, she
tried to hide it. The couple would make love and no matter what
Frank Woods tried, she couldn't feel it.

"He would ask me, 'Did that feel good?' and I would say, 'Oh, yes.'
But it didn't," Belt said yesterday. "Then, finally, I had to tell him the
truth.

"One day he was doing it to me and I said, 'Frank, I can't feel it at
all,' " she said. "I was devastated and upset."

Belt's lack of feeling stemmed from a past medical problem.

Together, they sought help and eventually found a doctor with an
answer to their problems - Viagra. Yes, Viagra, the anti-impotence
drug that caused a firestorm last spring after the Food and Drug
Administration approved its use for men.

Although the drug has yet to be approved for women, some women
are conducting their own private experiments with it.

Some such as Karen Brash, a Cherry Hill-based sex therapist, have
dipped into their husband's supply. Others get theirs from friends.
Then, there are those like Belt who go to the doctor and get their own
prescriptions.

"They come in and say, 'My husband is on Viagra . . . and I'm either
having pain or tenderness or dryness and it's just not happening for
me and I need some help,' " explained Dr. Steven Lamm, author of
"The Virility Solution."

"Women are saying, 'I want something and I want something now,' "
said Lamm, who has prescribed Viagra for some of his patients,
including a 38-year-old just yesterday.

Some women have amazing reactions to it. Belt took two Viagra
tablets last week and for the first time in a year, she could actually feel
it when her boyfriend stimulated her.

"It felt good again like it used to," she said. "Just to be able to feel
what he was doing to me, it was wonderful."

Kaye Renshaw, a Texas woman who began having sexual problems
following a hysterectomy four years ago, also has had good results.

"I was very excited with the changes I experienced even with the first
use," she said yesterday. "When I use the Viagra now in comparison
to when I don't, there's a night-and-day difference in the intensity of
the orgasms.

"I can still be orgasmic without it, but it's not nearly as intense or as
enjoyable without it," said Renshaw, a clinical sexologist. "And my
partner can also tell a big difference."

Doctors say their responses are typical.

"They report increased lubrication, increased engorgement and
increased sensitivity and ease in reaching orgasm," said Laura A.
Berman, a sex therapist, who along with her sister, a urologist, runs
the Women's Sexual Health Clinic at Boston University Medical
Center.

Since July, her clinic has prescribed Viagra for about 50 women,
including Belt. They are mostly cancer survivors, victims of pelvic
trauma in biking and other accidents, women who've had
hysterectomies and post-menopausal women.

"Most of the women Viagra tends to work best on are women who
were functioning before and now are not," Berman said. "Viagra is
not a desire pill. It's not an aphrodisiac."

"You could take Viagra and watch a documentary about snails and
nothing would happen," she said. "All it does is increase what would
naturally happen with arousal. You're not going to become aroused
just by taking the pill."

"It simply increases blood flow to the genitals and increases smooth
muscle relaxation," Berman said. "That means the vagina can relax
and lengthen and that's necessary for arousal and orgasm to occur."

As with men, not everyone is a good candidate for Viagra. Those on
certain medications, particularly those containing nitrates, should
avoid Viagra. More than 130 Americans who took Viagra have died
since the drug hit the market, but the FDA stresses that there's no
proof that the drug caused the deaths.

Some people on Viagra experience side effects, including facial
flushing, blurred vision, headaches, stuffiness and other discomforts,
experts say.

Brash, the Cherry Hill psychiatrist who experimented with some of
her husband's Viagra, was so uncomfortable after she took Viagra
that she doubts she'll do it again. "It was the usual good experience
except for a headache," said Brash, who has normal sexual
functioning.

Carol Brietzke feels the same way. About 45 minutes after taking
Viagra as an experiment for a Cosmopolitan magazine article, she felt
the pill begin to work. "I started to feel almost like the heat you feel in
your face when you blush," but in more intimate areas.

"Having that happen made me feel aroused . . . So, that was nice.
Then I had the hypersensitivity where he had to be a lot more gentle,"
Brietzke added. "Everything had to be feathery light. I didn't want
biting or anything."

"I had an orgasm but it wasn't anything unusual or remarkable in any
way. And then I had a headache. And I felt just kind of dizzy. I
thought 'I wouldn't do it again.' "

Then, she got a headache that lasted for nearly two hours. "It wasn't
debilitating, and I didn't have the blue vision. My vision was fine," she
said. "It was just kind of faintly unpleasant.

"I didn't like it all really," Brietzke said. "It kind of made me feel not
quite myself."

Another complaint that some women had was that they continued to
feel aroused even after they've climaxed, said Dr. Susan C. Vaughan,
a psychiatrist and author of "Viagra: A Guide to the Phenomenal
Potency-Promoting Drug."

"They were sitting at dinner feeling bothered by their continued
arousal," she said.

Pfizer, the drug's maker, said women shouldn't be taking Viagra,
anyway. "We certainly don't think it's a good idea to prescribe a drug
for a population in which it has not been tested," said Mariann
Caprino. "The only time people should use it is when the FDA
[brands] Viagra for use as a safe and effective therapy for feminine
sexual dysfunction.

"We still have a lot to learn as to how it should be used, when it
should be used, whether it should be used and if it should be used,"
she said.

There are a number of trials already under way in Europe, plus testing
in the United States, she said.

Meanwhile, many women like Renshaw, who's threatening to buy it
on the black market if she has to, will continue to take Viagra.

Belt, an Indiana factory worker, said it has done wonders for her
relationship. She was often depressed and moody and Woods had
threatened to leave on a number of occasions.

And she'd felt compelled to turn down her boyfriend's repeated
requests to marry her.

"I didn't have any idea how I could be his wife if I couldn't respond to
him. I told him I wanted to be able to feel him make love to me on his
wedding night."

Now, that she's enjoying sex again, the couple's planning to marry
sometime in June.

"When I first heard about Viagra, I thought, 'Wow, great. They've
got something to help men.' I never dreamed that it could help
women," Belt said.

phillynews.com



To: BigKNY3 who wrote (7033)2/18/1999 12:16:00 PM
From: Anthony Wong  Respond to of 9523
 
Celebrities help sell prescription drugs
February 17, 1999

NEW YORK (AP) -- Former presidential
nominee Bob Dole admits that he takes Viagra.
The perfectly composed Joan Lunden suffers from
itchy eyes and sneezing. Denver Broncos running
back Terrell Davis fights migraine headaches.

No, these people aren't attending a self-help group
for celebrities with ailments. They're helping
drugmakers pitch their medications.

As competition in the drug industry intensifies and
pressure mounts on companies to build profits, an
increasing number of pharmaceutical firms are
employing famous actors, politicians and sports
stars to attract consumer and physician interest.

"The use of celebrities is the next big way to
differentiate a drug," said Kelly Peters, senior
marketing manager for IMS Health, a health
information firm based in Plymouth Meeting, Pa.

Celebrity product endorsements are nothing new:
"Seinfeld" co-star Julia Louis-Dreyfus touted hair
color and Michael Jordan sells telephone service.
But until last year, drugmakers did not use them to
market to consumers because the industry's sole
focus was on promoting their products to doctors
who prescribe the medications.

The emergence of celebrity drug advertising -- to
patients and physicians -- comes amid an explosion
in consumer advertising since the Food and Drug
Administration in August 1997 loosened restraints
on television and radio commercials for prescription
drugs.

Last July, Schering-Plough became the first
pharmaceutical firm to use a celebrity in a
direct-to-consumer national television campaign. It
tapped Lunden, former "Good Morning, America"
anchor, to promote its prescription allergy pill,
Claritin.

The company would not reveal how much she was
paid, though analysts have speculated it's about $1
million a year.

The payoff for Schering-Plough: Claritin worldwide
sales soared by 35 percent last year to $2.3 billion,
including $1.9 billion in the United States.

"We saw this as the next step to reach out to
consumers," said Schering-Plough spokesman Bob
Consalvo.

Despite their increasing use, celebrities ads still
represent only a tiny portion of the billions the
industry spends on drug promotion each year. Drug
companies still rely on thousands of sales agents to
persuade doctors to use their drugs, said Ed
Mathers, vice president consumer health-care
marketing for Glaxo Wellcome.

But the use of celebrities shows how
pharmaceutical firms have become more creative in
their marketing. For example, Schering-Plough
advertises Claritin on United Airlines baggage tags
and Merck offers patients a money-back guarantee
on its cholesterol-lowering drug Zocor.

Drug companies use different types of celebrity
pitches to sell their products. In some instances,
they use those who can give a firsthand testimonial
to the effectveness of the drug, as Lunden did with
her hay fever treatment.

Other companies use public figures to raise
awareness of an illness to spur visits to a doctor for
treatment.

For instance, Pfizer, maker of Viagra -- the only pill
available for treatment of impotence -- will launch
an educational campaign on the disorder later this
month featuring former Senate Majority Leader
Dole. Dole, who has acknowledged taking Viagra,
won't mention it by name in the ad.

Yet in other instances, the celebrities are hired guns
who use their reputation to pitch specific drugs.

Merck, the world's largest drug company, hired
baseball star Cal Ripkin to promote the company's
Prinivil hypertension drug in ads that appear in
medical magazines. Ripkin, as the ads disclose,
does not suffer from high blood pressure.

"Cal symbolizes hard work and a solid work ethic,"
said Merck spokesman John Bloomfield. "And
Prinivil provides hard work ethic against a disease."

Mickey Smith, professor of pharmaceutical
administration at the University of Mississippi, said
the celebrity's believability is key to making such
campaigns work.

"The ads have to make sense," he said.

Two celebrities who suffer from migraines are
working with drugmakers to inform patients that
new treatments are available. Actress Jennie Garth,
of "Beverly Hills, 90210" fame, was hired by Glaxo
Wellcome, which sells the leading migraine
medication Imitrex. Novartis has contracted with
Davis of the National Football League to talk to
groups about his experience with its Migranol drug.
Davis used the nasal spray during the 1998 Super
Bowl, which the Broncos won and Davis was
named Most Valuable Player.

Another example: Novartis Pharmaceuticals hired
Maureen Reagan, daughter of former President
Reagan, to increase public knowledge of
Alzheimer's as it prepares to launch Exelon, a drug
that delays the onset of the disease.

"We wanted a spokesperson to be someone with
personal experience," said Novartis spokesman
Harry Hohm.

Celeb Ads

Some celebrities and the marketing campaigns they
have conducted for pharmaceutical companies:

-- Olympia Dukakis: The actress was hired by
Novartis Pharmaceuticals for its osteoporosis
awareness campaign. Dukakis has the bone loss
disease.The company sells Miacalcin nasal spray
for the condition.

-- Gavin MacLeod: The actor led a consumer
awareness campaign about impotence for Vivus
Inc., which markets Muse, an anti-impotence drug
given by injection. MacLeod did not personally use
Muse.

-- Stephanie Powers: The actress was hired by
Alza Corp., maker of Ditropan XL, the first
one-a-day overactive bladder treatment, for a
public awareness campaign. Powers does not
suffer from overactive bladder.

-- Kirby Puckett: A Minnesota Twins baseball
player until his career was ended by glaucoma, was
hired by Pharmacia& Upjohn to help the company
raise awareness about disease that causes
blindness. The firm makes the glaucoma drug
Xalatan.

canoe.ca



To: BigKNY3 who wrote (7033)2/18/1999 12:25:00 PM
From: Anthony Wong  Respond to of 9523
 
Kin Blame Hartman Death on Drug: '20/20' Anntidepressant maker faces suit, says show
From: New York Now | Television |
Wednesday, February 17, 1999

By RICHARD HUFF
Daily News Staff Writer

he family of the late Phil Hartman is preparing a lawsuit
against the maker of an antidepressant drug that Brynn
Hartman was using when she killed her husband and herself,
according to a report on tonight's "20/20" (ABC, 10 p.m.).

Brynn shot and killed her husband, the former "Saturday Night
Live" cast member and star of NBC's "NewsRadio," the night of
May 28, 1998. Then, according to police accounts, she turned the
gun on herself as the couple's two kids were rushed out of the
house by friends.

An attorney for the Hartman family tells "20/20" tonight that the
antidepressant Zoloft, which Brynn was taking, played some role
in the murder-suicide.

Hartman family attorney Andrew Vicary tells "20/20's" Elizabeth
Vargas that Zoloft was the one new factor in Brynn's behavior
before the tragedy.

"What else was different?" Vicary says. "She was taking cocaine
before. She had taken it in the past. She had taken alcohol before.
She had never done this kind of thing [turning violent] before. So
what was different in this instance?"

Asked if it isn't possible that the family might be grasping at straws
to find something to blame for the tragedy, Vicary tells Vargas:
"Possible, not likely. This family has proceeded in a very cautious
and reasonable and methodical way. They've asked me to look
into it. Not to file some headline-grabbing suit in L.A. the week
after this happened."

Vargas told The News yesterday that Vicary specializes in
pharmaceutical cases.

To prove that the drug had any connection to Brynn's action that
night, Vicary will have the difficult task of proving that Zoloft
triggered the murderous rage, and not the alcohol or cocaine she
had in her system, along with the Zoloft, according to an autopsy.

Drugmaker Pfizer told "20/20" that it has received notice there
may be a suit filed, but to date it hasn't been served. The company
also said it is aware of "no substantiated evidence of a causal
relationship between this medicine and violent behavior."

Vargas and her producers had wide-ranging access to the
Hartman family for her story, which she started working on last
June, a month after the murder-suicide.

Family members and close friends first contacted ABC, she said,
because they were unhappy with the way the Hartmans were
portrayed in the media, specifically reports of Brynn as a
"coked-up wife."

Vargas says she spent hours viewing Hartman home videos,
reading letters between the couple, and talking to friends and
family, including the nanny who was one of the last to see them
alive.

One friend tells Vargas that in the months before the horrific
incident, Brynn was struggling with turning 40 and with her
difficulty in launching a show business career.

"I had an idea about the drug problems . . . but it seemed really in
the past," said another family friend, Julia Sweeney, a former
"SNL" cast mate of Phil's.

The Hartmans left behind two children, a 9-year-old son, Sean
Edward, and 6-year-old Birgen Anika. Vargas did not speak with
the children.

"Their peace now is that their parents are in heaven and that Brynn
was forgiven by God and that Brynn was very sick that day and
didn't know what she was doing," their nanny, Lorraine Blanco,
said. "And she would never do anything to hurt their dad. That's
what they believe. They really believe that their parents are in
heaven watching over them."

mostnewyork.com



To: BigKNY3 who wrote (7033)2/18/1999 8:34:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 9523
 
2/18 PFE Pfizer Inc Paine Webber reiterates buy, strong pipeline, strong product launch, target $156, still the favorite.

nordby.com