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To: Dan Spillane who wrote (1262)2/20/1999 6:59:00 PM
From: Anthony Wong  Respond to of 2539
 
Business is booming despite fears over genetically modified food, reports Nigel Hawkes
The Times
February 20, 1999

Biotech firms flourish amid the furore

FOR a community whose life-blood is optimism, it has been
a bad week.

Day after day in the furore over genetically modified
(GM)food, headlines have denounced Britain's
biotechnology industry as a danger to the human race.
Indeed the past two years have not been kind to the infant
biotech industry, the closest thing to betting on horses the
stock market allows, as several setbacks have sent prices
plunging.

Despite this, Britain is producing one new biotech company
every week. The BioIndustry Association estimates that
there are more than 460 small and medium-sized companies
operating in biotech, employing 40,000 people.

This makes Britain's biotech industry second only to that of
the United States in size. For a country often accused of
failing to cash in on its science, the growth of biotech
companies is proof that things have changed. The
association estimates that growth in the industry has been
averaging 20 per cent a year.

With Germany now making rapid progress in the field, the
last thing British industry needed was a loss of public
confidence brought about by the anxieties over GM food.
However, Iain Cubitt, of Axis Genetics in Cambridge,
where plants are being grown to make vaccines in their
leaves, says that most of the British companies are in the
healthcare rather than the food market.

But the current furore "doesn't help public confidence", he
admits. "It is damaging because it all gets lumped together.
If people realised that the insulin or the drugs they use are
produced by genetic engineering, they would feel better
about it. As it is, investors are starting to ask 'Are we
investing in something that isn't going to be acceptable?' "

Robert Mansfield, head of Vanguard Medica, a drug
development company based in Guildford, is chairman of
the association, and sanguine about the future. "I don't
believe the furore will be damaging in the long term but it is
confusing to the public," he says. Peter Fellner, chief
executive of Celltech, in Slough, says: "As far as we are
concerned, in drug discovery, there is currently no damage.
Our investors know it is a highly regulated industry but I
worry that there might be a negative spillover of sentiment
in ways you can't predict."

It is where the science of DNA collides with the culture of
food that problems arise. Unlike Germany, where the
concept of manipulating DNA - the stuff of life - raised
fears inspired by the Nazi era, Britain has provided a
secure cradle for biotechnology, without intrusive
legislation. But German fears have calmed just as anxiety is
rising here.

Public money is being poured into biotechnology in
Germany to make up for lost time and growth there is now
very rapid. Companies that have failed in the United States
are getting a second chance, thanks to German taxpayers.

Dr Cubitt's company is closer than some to turning
investment into profits, since one vaccine, for an animal
disease, is already undergoing trials.

Dr Fellner thinks the industry in Britain is evolving in a
similar way to that of the United States, where euphoria
tends to be followed by a dawning of reality. In a business
where share prices are determined by "newsflow", bad
news can have dramatic effects.

But it is hard to keep a biotech man down. "I think that
biotechnology is going to unfold wonderful prospects in
healthcare, in cancer, in replacement organs," Dr Mansfield
said. "I worry that the public debate has focused around
food and not on the future importance of the industry in so
many other ways."

Banning GM foods without proper scientific reason would
jeopardise Britain's position at the cutting edge of
technology, Tony Blair says today. Writing in The Daily
Telegraph, he says that biotechnology will be as important
in the 21st century as computers have been in the 20th.

sunday-times.co.uk:80/news/pages/tim/99/02/20/timnwsnws01024.html?2383892



To: Dan Spillane who wrote (1262)2/20/1999 7:03:00 PM
From: Anthony Wong  Respond to of 2539
 
Scare given short shrift by knight of the scientific realm
Rachel Campbell-Johnston meets Sir Robert May

The Times
February 20, 1999

THE Chief Scientific Adviser to the Government defies
easy stereotypes. Whitehall mandarins are meant to be dull
and dispassionate, scientists introverted and
incomprehensible. Sir Robert May is outspoken, informal
and enthusiastic.

Sir Robert, 63, may have stayed backstage after he took up
his role in 1995, but such diffidence has nothing to do with
timidity. Last Monday, on Radio 4's Today programme, he
responded to scaremongering over a genetically modified
potato that had harmed laboratory rats by declaring: "If you
mix cyanide with vermouth in a cocktail and find that it is
not good for you, I don't draw sweeping conclusions that
you should ban all mixed drinks." His delivery captured the
public's imagination.

All week, journalists have been trying to get through on Sir
Robert's telephone, thrilled to have unearthed the scientist
who whispers in the Prime Minister's ear. He has resisted
demands for an encore. "It's better that the whole
community's voice should be heard," he explains. So why
did he agree to this interview? "I see no harm in people
having a sense of who I am . . . Actually, it would be quite
helpful if some members of Government found out who I
was."

For this Australian-born scientist, stuffy formalities are
there to be turned on their head. A knighthood is an
"extremely useful thing to whack in front of your name".

He is shuttling back and forth across his office, a slight,
restless, man, hands flying to his professorial hair. He is
exasperated by a Daily Mail front-page that shouts: "GM
foods: How Blair ignored our top scientists". It was a
"grotesque misrepresentation", he explains for my purposes.
But despite anxious interventions by his staff, he lets me
overhear less politely put opinions offered over the
telephone.

He thinks the present debate about GM foods doesn't
benefit anyone except the press. "Why suddenly discuss it
now? The origins of gene cutting were in the 1970s - I had
a big part in it. It has been blown up by the papers now in
large part because of BSE."

The telephone rings yet again - "Yeah, you bet, you bet. . .
like a bunch of bloody children," he tells the caller - and
returns to the interview with a cheery clap of his hands.
"Good, now I'll sit down and calm down." And suddenly his
charm and intellect are sharply focused.

A few days ago, he tells me, he had been sitting around a
table with the Prime Minister and a young woman from the
policy unit, and was impressed that the discussion was
simply a conversation between equals. Yet he pounces,
instinctively one suspects, on lazy reasoning.

I am treated to unfaltering disquisitions on anything from
theories of superconductivity (he assumes that I am familiar
with that) to poodles (he once had a pet one, dearly
beloved); from Fermat's Last Theorem (which he explained
to the Queen - "Don't worry, there won't be a quiz," he
reassured her), through religion ("I was brought up
Presbyterian but underwent an inverse epiphany at 13, and
now I'm irreligious") to opals (two serve as his cufflinks -
and there are three types, you know . . .).

He speaks candidly of a childhood of "genteel poverty" in a
suburb of Sydney, of how his mother divorced his father
because he was an alcoholic, and how he, as an asthmatic,
amused himself with mental puzzles and games of chess.
One day "something went snap" and he realised he was in a
different league from his schoolmates. "I had an
extraordinary undergraduate career," at Sydney University,
he tells me. "I topped every class for every subject."

The statement appears neither arrogant nor naive, more a
simple recognition of fact. Sir Robert may joke that the
cleverest thing he ever did was to marry Judith - they met
on a blind double date - but he well knows that his intellect
has earned him a remarkably varied and influential career.

He has been a theoretical physicist in Sydney and a
professor of biology at Princeton. He has used his
mathematical abilities to predict population changes among
animals, insects and viruses - and despite vociferous
criticism at the time, accurately forecast the effects of HIV
in Africa. He is also known for applying chaos theory to
biology, and subsequently explained the concept to Tom
Stoppard who wove it into his play Arcadia.

So what makes a great scientist? "Well, when I was an
undergraduate," he says, "I swotted like mad when it came
to exams, but otherwise I was more interested in snooker
and inventing funny forms of chess with my friends. I
realised that a researcher is essentially playing games
against nature, playing games with nature, where the nature
of the game is to work out what the rules are. I think that's
a good description of what motivates many scientists: the
sheer pleasure of the chase."

Science is so strong in Britain, Sir Robert believes, because
of the unhierarchical way it is practised. "British science is
infested with the irreverent young," he says.

"Anyone who thinks their life will be successful just
because they are bright is deluded. It's chance and
necessity that shape a career." His own career was partly
patterned by accident: the sudden death of his supervisor
led him to leave for America; he stumbled into ecology
after picking up a book on the subject.

But this happy-go-lucky attitude appears to be founded on a
bedrock of ambition - a driving desire for recognition. Sir
Robert takes pains to explain that his knighthood did not
simply come with the job, and that the most notable among
his many awards, the 1996 Crafoord Prize, is equivalent to
a Nobel - but because it is named after the family who
endowed it, lacks the resonance. "I feel quite irritated," he
says, teasingly adding: "When I was asked at the ceremony
what I was going to do with the money I told them I was
going to buy a flat in Chelsea. 'What a change from the
sanctimonious answers I usually get,' the woman said."

He lives in that flat during the week, and at the weekend
returns to his Oxford home, where he relaxes by jogging,
playing Real tennis ("a silly bugger's game), and reading -
anything from "detective rubbish" to bridge problems. "I'm
not a self-reflective person - I like doing things."

sunday-times.co.uk:80/news/pages/tim/99/02/20/timnwsnws02023.html?2383892



To: Dan Spillane who wrote (1262)2/20/1999 7:11:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 2539
 
GM foods: we stand firm, By Tony Blair, Number 10 Downing Street
The Daily Telegraph
Saturday 20 February 1999

Genetic science hailed by Blair

STANDING in front of a stampede is never a nice business. But occasionally
it has to be done. Parts of the media, and the Conservatives, have conducted
such an extraordinary campaign of distortion about the great GM food saga
that it's hard to know where to begin. Anyone who has dared to raise even the
smallest hand in protest is accused of being either corrupt or a Dr Strangelove.

Let's get one thing straight to begin with. In terms of its own interests as a
government, or my interests as Prime Minister, there is nothing in this for us,
other than a desire to get it right. This Government is fully committed to
ensuring the safety of food. That is why we will set up an independent Food
Standards Agency, and why we put the consumer first.

What is at stake is important. If we were to allow unsafe food into Britain, the
consequences of that are obvious; and no responsible government should ever
ignore any genuine risks to health. If, on the other hand, we were to ban GM
foods or crops, without any proper evidence to support such a decision, people
should start understanding the risks of that course, too.

We are committed to consumer choice. That is why this Government is
insisting on labelling that works. Before May 1997, the Tories blocked moves
to have clear labelling of GM food. If consumers don't want to buy GM, that is
fine by me. If suppliers don't want to use GM produce, they can use the list
that this Government produced to get non-GM ingredients.

Genetically modified food is just one branch of bio-technology. I am no
scientist, but those who are make what seems to me a compelling case that
biotech will be the revolutionary science of the 21st century. Britain has been
at the leading edge of this new science. Other countries are putting billions into
research. An area one-and-a-half-times the size of Britain is already under
commercial cultivation. There is no scientific evidence on which to justify a
ban on GM foods and crops. If we were to ban products that our independent
scientific advisers tell us are safe, we would send a negative message to the
whole biotech industry in Britain - that its future will be governed by media
scares. And we would stop British expertise in farming and science from
leading the way.

None of this means that we go ahead regardless. These are very reasonable
anxieties and we have a huge responsibility to act only in the interests of
people, not of vested interests of any kind. But all this is a reason to proceed
with great caution, evaluating each product before it can be planted, tested or
put on the market. It is not a reason for yielding to scaremongering.

For those who retain an interest in the facts, here they are as they seem to me.
Genetic modification of food by cross-breeding within one species of crop has
been going on for years. But, for the past 10 years, the science of molecular
biology has started to allow us to break down the genetic print-out of all living
matter and isolate a single gene; and it has allowed us to move genes across
species, not just within a species.

So scientists can isolate a gene in an animal and insert it into a plant. These
genes are used, for example, to make plants tolerant to pesticides that will
allow the plant to survive, but the pest to fail; or to improve the quality or
longevity of certain fruits or vegetables. The potential of such science is
obvious. It could revolutionise food production, making it cheaper and better,
and bring environmental benefits. Currently, farmers pour tons and tons of
pesticides over their crops. Some types of GM will mean that farmers need to
use much less.

But - and it is a big but - what effect does all this have on the environment, in
particular bio-diversity? Crossing genes within a species is one thing; across
different species is another. Already such genetic modification is used in
medicine - insulin, the drug for diabetics, is GM - but does it have unforeseen
consequences for food? There is, neither here nor elsewhere, any actual
evidence that there are such harmful consequences for food safety. But,
rightly, people want to be sure.

For these reasons, no GM food is sold in Britain without going through an
elaborate regulatory procedure. Three such GM foods have been licensed, all
before the last election. Since the election, we have also insisted on labelling
for GM food, reversing the previous government's position. There are no
commercially exploited GM crops in Britain at the moment. There are,
however, limited farm-scale trials to test them. This is primarily to check the
effects on bio-diversity. All the tests will be verified, then assessed, again by
wholly independent scientific experts.

Let me now correct the past two weeks of misinformation, which can't have
done the media's credibility any good at all. It is said that English Nature
demanded a moratorium on GM food. Wrong. It asked, on environmental
grounds, for a three-year moratorium on the widespread commercial growth of
GM crops that are tolerant to herbicide, until the trials are finished. Our
response is to point out that each crop is being tested on an individual basis and
that the trials should last as long as they take.

It is said we suppressed a report on the risks to farmland wildlife. Wrong. It
was being considered in the normal course of events by our expert advisory
committee and was published last Thursday. It is said we have ignored the
findings of the Royal Society, the country's most eminent scientific body, on
GM foods. Wrong. We are acting on its recommendations. So intensive have
these stories been that we have published a point-by-point rebuttal of every
one of them on the Internet. And, of course, some papers now say the
Government has failed to reassure the public - having spent two weeks doing
their damnedest to make sure the public never got near the facts - when the
Government's position has not changed from the beginning of this saga to the
end of it. The Conservatives have waged war on Lord Sainsbury, continuing
their peculiarly unpleasant personal attack on ministers as a substitute for
serious opposition. There is no conflict of interest in David Sainsbury's position:
he has nothing to do with the licensing of GM foods.

Two broader issues occur to me. The first is the importance of the
Government not yielding to an orchestrated barrage on an issue of long-term
importance. On matters that emerge from advances in our understanding of
the natural world, we need to be guided by good science, not scaremongering.
It is the only way, in the end, to govern in the country's interest. The second is
that we should resist the tyranny of pressure groups. Just because an
organisation calls itself "green" doesn't mean to say that we all have to do what
it says or that we are destroying the environment. But I promise to listen to
those with real concerns, with evidence and facts. Rational and informed
debate is what this whole matter should be about. Despite the past two weeks,
I believe, in the end, that reason will prevail.



To: Dan Spillane who wrote (1262)2/20/1999 8:21:00 PM
From: Anthony Wong  Read Replies (2) | Respond to of 2539
 
Australia - Loopholes feed doubt
By MARY VISCOVICH
The Herald Sun
Sunday 21 February, 1999

ALMOST half the food on our supermarket shelves contains some sort of
genetically modified "mutant" food, say Australian nutritional experts.

But loopholes in the law mean there is almost no way for consumers to know
which foods are affected.

Opponents of the genetically modified products – or "Frankenfoods" as they have
been dubbed in Britain – say too little is known about possible long-term risks and
say increases in cancers and immune deficiencies could result.

A scientific panel in Europe has confirmed evidence from a Scottish study that
genetically modified food had shrivelled the brain and other organs of rats.

As debate on modified foods rages overseas, most Australians already regularly
consume such products.

The foods have been appearing on supermarket shelves over the past two years
because there has been no legislation to prevent it.

Soybeans, the wonder crop of the '90s, are being grown from genetically modified
pest-resistant plants and processed into soy by-products used to enhance
everything from baby formula to margarine and lollies.

Fish and chips are already being cooked in genetically modified cottonseed oil.

Consumer and health groups this week raised concerns over the recommendation
by the Australia /and New Zealand Food Authority (ANZFA) that Roundup Ready
Soybeans and Ingard Cottonseed can be sold here. They were the first modified
foods for which approval was formally sought, although both are already in shops.

Authority spokeswoman Lydia Buchtmann assured consumers yesterday that
modified foods already on the shelves were safe.

"They were assessed under existing food laws which prohibit the sale of unsafe
foods," Ms Buchtmann said.

"These foods have been tested in the US and Europe, and have been on the market
for a lot longer than they have been here."

Ms Buchtmann said health ministers last July gave a nine-month period of grace for
introduction of new standards for genetically modified foods. They decided all
modified foods would have to be labelled, but legislation has not yet been passed.

"Any genetically modified food which does not have approval by May 13 will have to
be removed from shelves," she said.

Bob Phelps, director of the Melbourne-based consumer health group the Australian
GeneEthics Network, said that if applications by industrial giant Monsanto were
approved for genetically modified corn, canola, cottonseed and soy, up to
90percent of supermarket food could be affected.

Corn starches, other corn by-products, canola oil and cottonseed oil can be found
in almost all processed foods.

"People should talk to their health ministers and tell them we don't want it," Mr
Phelps said.

Genetic modifying involves the transfer of genes between different species. Plants
can receive animal genes and animals can receive human genes.

Experts say it can boost world food production through pest-resistant crops and
giving greater shelf-life to foods.

But Mr Phelps said the lack of regulation meant companies which sold modified
foods did not have to label them. The companies were also trying to resist the need
to label modified sugar, oils and enzymes such as yeast found in beer and bread.

"Fifty per cent of the food on supermarket shelves contains genetically modified
ingredients, while 100,000 tonnes of genetically modified soybeans are imported
from the US each year," he said.

"I think (these) foods will be allowed into this country but the issue of labelling is
not negotiable. People have to have some sort of control over what they are
buying."

Mr Phelps said the danger lay in the DNA of modified food being transferred to
humans.

This could lead to problems such as resistance to antibiotics, changes in structure
and make-up of food, and a narrowing of bio-diversity, which would see the virtual
extinction of types of foods which contained vital disease-fighting properties.

"Certain types of these plants have been bred to kill insects, there is no reason to
assume they can't harm us. We just don't know yet," Mr Phelps said.

Nutritionist Rosemary Stanton also called for caution.

"People are moving forward with unholy haste to do this and I don't know why," she
said.

But Ms Stanton, who is on the steering committee of a special congress on the
subject to be held in Canberra next month, said she believed the technology should
not be thrown out.

If it was used to put a hepatitis vaccine in a banana which could be easily
distributed in the Third World, it was obviously of benefit, she said.

Genetic food giant Monsanto yesterday stood by its products.

"These technologies allow plants to be grown in better ways with less impact on
the environment," said Monsanto spokesman Nick Tydens.

"Down the track we will see things like potatoes which will absorb less fat when
they are fried, foods with higher vitamin content and, particularly valuable in Asia,
rice with higher levels of vitamin B-12," he said.

He said scare campaigns were being waged in Europe, even though the foods had
been assessed and approved in 20 countries.

"Most of the products would have about 1percent of genetically modified foods in
them, a tiny amount which makes very little difference," Mr Tydens said.

"We think people should be well informed, not scared."

Peter Langridge, Professor of Plant Science at the University of Adelaide and
member of the Genetic Manipulation Advisory Committee which reports to the
Federal Government, also said he was alarmed at the direction the debate was
taking in Europe.

"There is a large group of people who live off keeping people frightened and there are some very serious errors of fact," Prof. Langridge he said.


"There needs to be a debate, but it's crucial that the information we have is
correct."

He said he supported clear labelling of modified foods, but was confident that
whatever made it to our tables was safe.


theaustralian.com.au