To: Q. who wrote (2102 ) 3/16/1999 5:57:00 PM From: Anaxagoras Respond to of 2506
<<Biotechs often trade at a certain multiple of market cap to cumulative R&D expenses. If that ratio is 20 or 50, then there's good reason to look to see if it is highly overvalued. Maybe they are not doing much R&D, and just producing hype. If the ratio is 1, then I would forget the stock as a short candidate unless I came up with something else that was really ugly, as Asensio did with HEB. >> This was truly a fine post John, and it's well worth re-reading. Thanks. Just to add a little bit more, I was just e-mailing some folks about HEPH and how they stacked up on the ratio you mention (HEPH is getting a lot of press at the moment, got a write-up over on TSC the other day). In doing so, I recalled Dale's questions from a while back, and so I came over hear to re-read some stuff, and thought that this might be of interest, FWIW. Here's what I wrote: Just for fun I computed the M Score for HEPH. This is a Michael Murphy metric that he uses to compare valuations of developmental companies. All that's involved is dividing market cap by the total R&D spending for the last five years (anything older than this probably isn't worth much). HEPH is on a calendar year and it hasn't yet filed its 10K, but as of September 30, 1998, the company had only racked up about $7.2M in total R&D since its inception back on August 15, 1994. Today it ended with a market cap of roughly $176M, so that gives us a lofty M score of > 24. FWIW, here's what Murphy says in his book about the ranges for this number:<<M Scores range all over the map, from under 1x, where you are buying into the technology for much less than the venture capitalists spent to create it, to 40x or more. Like growth-flow multiples, M Scores in the 10x to 12x range are typical. Under 8x is interesting, under 5x is compelling, and under 3x- there are many of them around these days- means that if the science works you will make lots of money. At under 3x, you often pay less for the stock than the venture capitalists paid in the last round of private financing. Check the company's initial public offering prospectus under "Certain Transactions" to see what the venture capitalists paid.>> P. 152 Anaxagoras