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Biotech / Medical : STEM -- StemCells, Inc. -- Ignore unavailable to you. Want to Upgrade?


To: WWS who wrote (212)2/25/1999 4:16:00 AM
From: Mike McFarland  Read Replies (2) | Respond to of 805
 
Although techniques for practical clinical harvesting
and expansion are well developed for human hematopoeitic
stem cells, I'm not sure how much comparable progress has
been made for human neural stem cells.


I was too sleepy earlier today to repost the PR from ctii
from back in December...so here it is for newbies. I know
this does not answer all your questions Bill, and we probably
already went around with this issue in the previous hundred
posts, but I'll leave this here for anybody new to the thread.

CTII neural stem cell patent...
No. 5,851,832, covering methods for expanding human neural stem
cell cultures, for compositions of human neural stem cell cultures
expanded by these methods, and for use of these cultures in human
transplantation and remyelination.
(snip)
In preclinical studies, the Company's scientists and
collaborators have already demonstrated the ability to:

characterize, proliferate and differentiate human neural
stem/progenitor cell cultures in vitro; engraft human neural
stem/progenitor cells into the brains of rodents where the
cells differentiate into the neuronal lineages characteristic
of the site into which they are transplanted; engraft human
neural stem/progenitor cells into the spinal cords of myelin-
deficient rodents in a model of multiple sclerosis where the
cells differentiate into myelinating oligodendrocytes; and
genetically modify multipotent adult rodent hippocampal neural
stem/progenitor cells to differentiate into neurons and glia.
(snip)

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