BOSTON CAPITAL Lowering the boom By Steven Syre and Charles Stein, Globe Staff, 02/25/99
If philosopher George Santayana was right, and those who forget the past are doomed to repeat it, then this may be a good time for a history lesson. Set the wayback machine for the early 1990s, Sherman. We're going back to the biotechnology boom on Wall Street, a development with some eerie parallels to the current mania for Internet stocks. Notes Katherine Kirk, an investment banker with Hambrecht & Quist in Boston: ''Investors are in love again.''
Biotechnology stocks took off in 1990 when one of the industry's leaders, Amgen Inc., produced the first biotech blockbuster, a key drug for kidney dialysis patients. For investors the message was clear: Biotech was ready to move from the laboratory to the marketplace. Diseases would be cured; money would be made. Hardly any biotech companies were making money at the time, but that didn't matter. Profits took a back seat to potential.
Amgen's stock price rocketed from 7 to 78 in a short period of time. In 1991, Fidelity's Select Biotechnology fund climbed an astounding 99 percent and its assets ballooned from $70 million to $1.1 billion in less than two years. It looked as if the sky was the limit.
Only it wasn't. In early 1992 the stocks started to tumble as investors questioned some of their early assumptions. And in the spring of that year, when the US Food and Drug Administration refused to approve drugs from two of the highest-flying biotech companies, the rout was on. The stock price of Centocor Inc., one of the spurned companies, fell from 60 to under 10.
Biotechnology didn't disappear. A handful of companies, including Amgen, have gone on to become large, profitable businesses.
But investors never made the kind of money they dreamed about in those heady days. The Fidelity biotech fund, for instance, has less money in it today than it did at the peak in 1991. Hambrecht & Quist's own biotech index is no higher than it was back then.
''It's as if we had a wild New Year's Eve Party and the hangover lasted years,'' says Brian Stack, portfolio manager of MFS New Discovery fund.
Investment pros who lived through both periods will tell you there are important differences between biotechnology and the Internet. Biotech's progress in bringing products to market was agonizingly slow; the Internet seems to grow at lightspeed. Biotech had the potential to change medicine; the Internet may yet change every business it touches.
But there are parallels between the two booms as well, say money managers. And perhaps a few cautionary lessons too. What can we learn from studying the biotechnology bubble?
1. It's hard to pick the ultimate winners at the beginning.
Imagine you are a farmer planting seeds in the spring. Can you say, at that point, which plants will grow tall and straight and which will never sprout? An investor evaluating companies in an emerging industry is in much the same position.
''You are dealing with a new technology and no one knows how the story will play out,'' says David Stone, who followed biotechnology stocks for the Boston office of Cowen & Co.
Amgen and Centocor were both early biotech leaders. One soared, the other stumbled, at least until recently.
And Biogen Inc., a Cambridge company that has been a Wall Street favorite, didn't come on the radar screen until 1996.
2. Sometimes it's even hard to know who the players are.
Investors assumed that biotechnology was a world unto itself. They were wrong. At the same time biotech companies were busy in their labs, the major drug companies were even busier working on blockbuster drugs for the future. With the benefit of hindsight, investors who believed in the promise of biotech should have been investing in companies like Merck & Co. and Pfizer Inc.
Similarly, the Internet is viewed today as a distinct field with distinct companies. But who is to say that the ultimate winners in the Internet competition won't be established names like Wal-Mart or IBM rather than Amazon.com and Yahoo?
3. Euphoria has a way of blinding people to risk.
In their enthusiasm for biotech stocks, investors failed to appreciate how long it would take to turn good ideas into marketable products. With the Internet, the risk may be just the opposite. Because there are practically no barriers to entry, just about anyone can jump into the Internet business overnight.
''We're dealing with a much fiercer competitive landscape,'' says Kirk of Hambrecht & Quist. In such a world, she says, competitive advantage can vanish as quickly as it appears. Which leads to an obvious question: Is that risk built into the price of Internet stocks?
4. Promise is not the same thing as profit.
Thomas O'Neill, chief investment officer at Fleet Financial Group Inc., says it was hard not to be excited by the potential of biotechnology.
''You were talking about curing diseases,'' he recalls. ''These were exciting things.''
The Internet has the same kind of buzz about it. Like biotechnology, it could change the way we live our lives. But eventually that excitement has to find its way to the bottom line. Companies don't have to make money in the early days. New firms can have valuations that look preposterous on the surface.
But down the road investors need to see a real return. Otherwise, as the biotech boom demonstrated, soaring stock prices can come back to earth in a hurry.
Red Herring
Matthew Nestor has been named director of the state securities division by Secretary of the Commonwealth William Galvin.
In his new job Nestor will manage the staff that regulates the offer and sale of securities. Nestor previously was chief of enforcement in the securities division.
''Matt Nestor is a respected figure in the fight against investment fraud in Massachusetts and nationwide,'' said Galvin.
Nestor is a graduate of Boston College Law School.
Steven Syre (929-2918) and Charles Stein (929-2922) can also be reached by e-mail at boscap@globe.com.
This story ran on page D01 of the Boston Globe on 02/25/99. © Copyright 1999 Globe Newspaper Company.
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