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To: scaram(o)uche who wrote (437)2/25/1999 2:44:00 PM
From: mike headRead Replies (1) | Respond to of 4974
 
Kinda complicated, maybe, but what the Hell... I'll plug in CTRX (thinking of Tex Dude). mch



To: scaram(o)uche who wrote (437)3/2/1999 4:09:00 PM
From: Jorgen JensenRead Replies (2) | Respond to of 4974
 
Submission for daily contest:

Tuesday March 2, 10:25 am Eastern Time

SOURCE: Medtronic, Inc.

Medtronic and Cognetix to Collaborate on Revolutionary New Approach for the Treatment of
Epilepsy

Treatment May Reduce Seizures Without Sedation and Functional Impairment

MINNEAPOLIS and SALT LAKE CITY, Utah, March 2 /PRNewswire/ -- Medtronic, Inc. (NYSE: MDT - news), and Cognetix, Inc., announced today that they will
collaborate to develop and commercialize a revolutionary new approach for the treatment of severe epilepsy. This new treatment is intended to reduce seizure activity
without the sedation and functional impairment common with many current epilepsy treatments. Terms of the agreement were not disclosed.

It is estimated that more than 2.5 million people in the United States suffer from some form of epilepsy. Approximately 20 percent of these individuals do not receive
adequate control of seizures with currently- available medications, leaving surgical intervention as the only therapeutic option.

In this collaboration, the Medtronic SynchroMed® Infusion System will be used to deliver a compound called Conantokin G (Con G) from Cognetix directly into the
brains of patients with epilepsy. Derived from Conus sea snail venoms, Con G is a conopeptide that may control convulsions.

In preclinical studies, Con G reduced seizure activity without the sedation and functional impairment characteristic of many current epilepsy treatments. Con G's
efficacy is based on its unique ability to target only those brain receptors that control seizures.