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Biotech / Medical : Don't Floss, You Lose - (ATRX) To the RESCUE. -- Ignore unavailable to you. Want to Upgrade?

To: patlew who wrote (59)	2/27/1999 11:24:00 PM
From: Arthur Radley	Respond to of 182

Lloy, I don't know exactly where you are going with your questions, however, on the surface it appears that you have reservations about the use of Atridox. Let me assure you that I'm not a medical professional, so I think it best to refer you to data that is provided by the company and data that the FDA used in approving this new treatment for this disease. If your purpose is to catch us in misinformation, I can assure you that is not meant intentionally. Therefore, I suggest you look at the company website at the following: atrixlabs.com ATRX clearly states that Atridox is an easy an effective option for treating before it reaches advanced stages and for maintenance therapy following extensive periodontal treatment. The Phase III clinical studies showed that Atridox produced better results in pocket depth reduction and attachment results, as compared with SRP. I might add that the FDA apparently found these study results valid as they approved the treatment. To get definitive answers as to "cases caught early" and "advanced case" you probably need to talk with a medical professional or at least give us your perception as to what each means to you. Then we might come to some agree. I hope that what I perceive in your post isn't the case. Maybe a response as to what your true feelings about Atridox are,then we might be able to respond more directly to your nebulous questions. As I've stated before, if you have reservations about the product, that is fine. Your enlightenment to these concerns will be appreciated, but don't try to trap us with your questions. Okay! (:>)

To: patlew who wrote (59)	2/28/1999 3:26:00 AM
From: Dan B.	Read Replies (1) \| Respond to of 182

I am a layman speaking as a layman. I am not at all prepared to define the phrase used by the AAP in it's statement; Yet it is clear to me that Antridox alone is considered equivalent to scaling and root planing, and further, it's use as an adjunct to that conventional treatment has not even been studied. The warning appears to be that in "advanced cases", the professional might not expect Antridox alone to do the job. No similar implication is drawn for cases other than "advanced"(however defined). While I'm sure a professional could answer your question, it's clear to me that they use the phrase "advanced cases" to imply conditions more severe than cases where "2.Atridox was clinically equivalent to scaling and root planing." Clearly they feel it may be a viable and equivalent substitute with the caveat that "the magnitude of expected results need to be considered by each practitioner in light of the severity of the defects being treated." On the possibly negative side, I WOULD say they hedge by saying "Long-term (>1 year) data regarding the stability of treatment outcomes are also not available." So they don't vouch for long term results. Still, nowhere that I can see do they imply that Antridox is only to be used as an adjunct to scaling and root planing. Quite the contrary, again, they say it's use as an adjunct in "advanced cases" ought to be studied. Perhaps this implies hope that combined treatment in such cases could provide positive results previously difficult or impossible to achieve. Also..."...The Academy is not aware of any data available regarding the need for further surgical or non-surgical treatment of sites after treatment with Atridox." In other words they have no basis to say whether treatment with Antridox alone works long term without further treatments. It may- but they just don't know.