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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?

To: Edderd who wrote (19188)	3/2/1999 6:42:00 PM
From: Mkilloran	Respond to of 23519

edderd...not a problem in Japan.... The Samurai sword is the best pill splitter and you can also cut your grapefruit with it as well.... Just waiting for more countries to license Muse, milestone payments and launch to get us to see real earnings ..... expect a good conf call in July....

To: Edderd who wrote (19188)	3/2/1999 7:16:00 PM
From: Zebra 365	Respond to of 23519

DaiS, I agree with Eddard, these pills are made in hundred gallon batches with filler and the whole batch must be extremely homogenous before the pills are pressed or molded. To suggest that the drug would be unevenly distributed in the pill is to suggest that the finished pills themselves would show an unacceptable variation in drug content due to assymetrical mixing of the batch. I said it before, any pill can be split as long as the whole pill does not constitute a drug delivery system. Because this is difficult for lay people to understand (the pills don't say when they are a "delivery system") the safest rule is to tell people to never split unscored pills. I just took a triangular file to a Viagra sample 50 mg pill, scored it, placed it on a flat surface with the score up and pressed on both sides of the score. It split fine. I'd bet that those halves would meet the FDA criteria for 25 mg Viagra. Now we return to your local VVUS stock, where Cap'n Wilson is said to have lashed himself to the mast. Zebra <<PS Did you meet such doctors when you were in Brecon!?>> DaiS The docs I met in Brecon were a fine group of docs. They could diagnose sharper with less reliance on equipment than their American counterparts. They had even come to terms with the NHS. But their kind of practice wouldn't work in America, Americans have given up religion and put their faith in machines. The more machines used in a person's diagnosis, the "better care" they have received here. And Americans would never wait for things like the Brits, Americans want the best care and they want it yesterday. I have people call me up the day after being given an antibiotic and demanding a consult with a specialist because they "aren't better yet".

To: Edderd who wrote (19188)	3/2/1999 7:30:00 PM
From: DaiS	Respond to of 23519

Ed, Well, I don't know what the big deal is.... It was a British doctor who brought the whole thing up damn it not me! Why did the Pfizer spokesman evade the question of distribution and instead suggest that there could be problem if pill were cut with dirty knife? I am sure that you and Zebra would remind your patients to use a clean knife! It makes me go cold just thinking about what might happen if a dirty knife were used...imagine if the man took a knife from the dishwater thinking it had finished, but really his wife had forgotten to switch it on after dinner? Pfizer did not confirm that the drug is evenly distributed in the pill because it would sanction the splitting, something that impacts negatively on their revenue...to leave doubt in the patients mind would contribute to the protection of their revenues. If us patients are naive and stupid not to realise that there is no problem splitting a pill what are we to say about the doctors cited in those news items. 50mg and 100mg the same price almost. Yes why is that? Could it be that Pfizer overpriced the lower dose pills because they suspected all along that this thing might happen? DaiS