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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?

To: Edscharp who wrote (9162)	3/12/1999 7:20:00 PM
From: aknahow	Respond to of 17367

First, let me say, I am glad you also survived long enough to make a post. I think this is probably the only trial with a pre established low overall survival rate. (D rate). This was done to permit reasonably quick trial conclusion even with a small number of subjects. Rick Harmon might know if this has been done before but he might think one is trying to hype Xoma if I asked him. It is really unusual and perhaps when everything is over we can get XOMA to tell us if it has ever been done before. Since, supposedly, there is nothing new under the sun, it may have been. But I think we are seeing history being made. And I would hope that in the future if they ever do it this way again, that deaths will only be required in the placebo group.

To: Edscharp who wrote (9162)	3/13/1999 8:41:00 PM
From: aknahow	Read Replies (1) \| Respond to of 17367

Ed, I asked your question on the LGND board. People on the VD Portfolio and BVF boards might know but have asked on neither yet since the question is apt to be misunderstood. Tried not mentioning XOMA on the LGND board and the first reply mentions the XOMA trial. BTW I know I am biased but I loved the Wisconsin hospital 30 yr. study saying one must be careful with overall mortality rates and that mortality has not varied over 30 years when mortality is measured by severity. (This is what I thought it said). Also does not mean it is still true. Also was impressed with the 30% when 8 or more on the Glasgow scale article. Don't know why it took so long to find this stuff and once one finds it one does not know that it is any more correct than the stuff one did not want to accept. But now that I have found the answers I want, I have stopped looking for anything that might cast doubt on them. Hope the trial ends soon. Can't take much more of this.