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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: Robert K. who wrote (9441)3/30/1999 9:52:00 AM
From: Bluegreen  Respond to of 17367
 
Bob, until we know more about the GNE and XOMA future relationship, I'd cool it. Those disclaimers may become worthless under heat.



To: Robert K. who wrote (9441)3/30/1999 1:50:00 PM
From: aknahow  Respond to of 17367
 
Robert, when you view this patent do browser search for XOMA. They have license agreement for one product described.
United States Patent
5,885,808
Spooner , et al.
March 23, 1999

Adenovirus with modified binding moiety specific for the target cells

Abstract

An adenovirus or adenovirus-like particle which has a modified binding specificity conferred by a binding moiety. The
binding moiety is heterologous to the adenovirus and is incorporated as a fusion protein with the fiber protein. This allows
the adenovirus or adenovirus-like particle to bind to a target cell which is not the natural host cell of the virus. The penton
fiber is modified by the insertion or, deletion, or substitution of amino acid residues, that disrupt the host-cell binding
function so that the adenovirus or adenovirous like particle does not bind the natural host cell.