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To: Boss Fan who wrote (6456)4/7/1999 11:22:00 AM
From: ciVic  Respond to of 13776
 
BOSS fan added more at 1.09 here....we in this together..

ALL buys at 1.09...

ciV



To: Boss Fan who wrote (6456)4/7/1999 11:23:00 AM
From: Jeffrey D  Read Replies (1) | Respond to of 13776
 
Biotech anyone? I'm in. Jeff

Bridge Technology Group Announces Investment Opinion on Megabios Corp. -Valentis, Inc.-

NEW YORK--(BUSINESS WIRE)--April 6, 1999--

Bridge Technology Group LLC Initiates Coverage of Megabios Corp.

(Valentis, Inc.) With a Buy Recommendation

Please Visit Bridge's Web Site at www.BridgeNYC.com

for Detailed Report

Bridge Technology Group LLC announced today that it has initiated coverage of Megabios Corp. (Valentis, Inc.) (Nasdaq: MBIO) with a BUY recommendation. The full text of this report can be accessed at Bridge's web site, at www.BridgeNYC.com.

Excerpts from the report follow:

Following the approval of the shareholders of both Megabios and GeneMedicine on March 18, we are initiating coverage of the merged company with a BUY recommendation. The new company intends to operate under the new name of Valentis, Inc., in the near future. We believe this merger was synergistic from a number of perspectives, and the resulting company is the clear leader in plasmid-based gene therapy using lipids as the means of gene delivery. Valentis has seven potential products in Phase I/II clinical trials, and 24 therapeutic genes in research or pre-clinical development, significant collaborative partnerships with Glaxo Wellcome, Eli Lilly, Roche and DSM Biologics, a combined intellectual property portfolio that should strengthen the new company's ability to compete in the gene therapy field, and a stronger balance sheet. Together, we feel Valentis has all the key technological components - gene delivery, gene expression and gene medicine production - to successfully develop and commercialize gene therapy and other products. We believe the company is significantly undervalued relative to comparable companies participating in the gene therapy field and are recommending purchase of the stock for those investors tolerant of the risks associated with small-cap, developmental-stage companies.

Impressive Clinical Product Portfolio - Seven Products in Clinical Trials

- Cancer Gene Medicines: Valentis has clinical trials ongoing with

Interleukin-2 (IL-2), IL-2 in combination with superantigen B,

and Interferon-alpha (IFN-) for treatment of head, neck and lung

cancers. Preclinical trials are also in progress on the

tumor-suppressing BRCA1 gene to treat breast and ovarian cancer

and an IL-12 gene medicine.

- Pulmonary Gene Medicines: Valentis has two clinical trials

underway currently - one to treat cystic fibrosis (CF) and one

that uses the alpha-1 antitrypsin (AAT) gene that is being

developed to treat AAT deficiency, a significant contributor to

the development of emphysema.

- Cardiovascular: Two clinical trials are ongoing in Finland using

Valentis technology to develop vascular endothelium growth factor

(VEGF) gene medicines. VEGF has been shown to induce

angiogenesis, and is being evaluated for use in the prevention of

reclosure of vessels in patients undergoing angioplasty.

Strong Corporate Partnerships - Strategy to Diversify Technology Portfolio

- Valentis has multiple, strong corporate partnerships to help

defray the high costs of drug development and spread the risk

over multiple programs in various therapeutic areas. Partners

include Glaxo Wellcome, Eli Lilly, Roche and DSM Biologics, a

leader in the manufacture and supply of biologics.

- We are impressed with management's vision to leverage its

expertise in gene delivery and create a company with a more

general focus on biologics delivery. This should serve to broaden

the Company's technology base and product pipeline, diversify

risk, and possibly shorten the timetable to product revenues

(should products be acquired or licensed further along in the

clinical process).

Compelling Valuation - Moving Forward from a Position of Strength

- As of the date of the merger, the combined company had cash and

cash equivalents of $50 million; management has expressed its

goal to reduce its burn rate to under $15 million per year during

1999 as a result of the integration of the two companies.

- With several years of cash available, we believe Valentis to be

in a position of great financial strength, a unique

characteristic of a development-stage biotechnology company. In

addition, versus its peer group, we believe Valentis to be

significantly undervalued based on the breadth and depth of its

product and technology portfolios.

Bridge Technology Group LLC is a registered investment advisor focused on identifying emerging growth companies in the healthcare and information technology sectors that offer compelling investment opportunities over the long term. By providing comprehensive financial services, including corporate finance, M&A advisory, strategic partnering and communications consulting, the company positions itself to provide a fully integrated package of value-added services to emerging growth companies.

The information in this press release has been obtained from sources that Bridge Technology Group LLC believes to be reliable, but the Company does not guarantee its accuracy or completeness. Neither the information nor any opinion expressed constitutes a solicitation by Bridge Technology Group LLC for the purchase or sale of any securities. Bridge Technology Group LLC has performed investment banking, consulting or other services for MBIO and may solicit investment banking, consulting or other business from, any company mentioned in this release. Bridge Technology Group LLC or persons associated with Bridge Technology Group LLC may at anytime be long or short any of the securities referred to herein and may make purchases or sales thereof while the Company's reports are in circulation or posted on the Bridge Technology Group LLC web site at www.BridgeNYC.com. This material, or any portion thereof, may not be reproduced without prior permission from Bridge Technology Group LLC. Bridge Technology Group LLC is not responsible for the contents of this document that is intended for electronic transmission and could be thus subjected to tampering or alteration. Copyright (c) 1999 by Bridge Technology Group LLC. All rights reserved.

CONTACT:

Bridge Technology Group LLC, New York

Jeffrey B. Davis

212/554-4158 (phone)

212/554-4058 (fax)

info@BridgeNYC.com

>>



To: Boss Fan who wrote (6456)4/7/1999 11:52:00 AM
From: Frederick Langford  Respond to of 13776
 
Jeff,
GCHC, I think this is just the beginning. Chinese Primere in US. WTO discussions. China's economy/capitalism on the front burner, JMO.

Fred