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Biotech / Medical : Cortex (Cor) [formerly CORX] -- Ignore unavailable to you. Want to Upgrade?


To: daveG who wrote (805)4/19/1999 9:32:00 AM
From: daveG  Read Replies (1) | Respond to of 1255
 
Cortex Pharmaceuticals' Experimental Drug for Schizophrenia Shows Statistically
Significant Effects in Cognition Improvement

Results Exceeded Our Expectations'

SANTA FE, N.M., April 18 /PRNewswire/ -- In a presentation at the
International Congress on Schizophrenia Research today, Donald C. Goff, M.D.,
principal investigator, reported results of a clinical trial with CX516 (Ampalex(R))
in 19 patients with schizophrenia. Dr. Goff is Director of the Psychotic Disorders
Program at Massachusetts General Hospital in Boston.

The double blind, placebo-controlled four-week study is intended to evaluate the
safety of combining CX516 (Ampalex) with clozapine, a commonly used
anti-psychotic medication. CX516 (Ampalex) is one of the new Ampakine(R) class
of drugs being developed by Cortex Pharmaceuticals, Inc. (OTC Bulletin Board:
CORX). Dr. Goff reported that Ampalex was well tolerated and did not induce any
significant adverse effects.

"Ampalex appears to have improved a number of aspects of cognitive function as
measured by a battery of neuropsychiatric tests," stated Dr. Goff. "Patients
receiving the drug exhibited improvements in performance on tests of verbal
learning and memory, problem solving, and distractibility. The magnitude of
improvement in the California Verbal Learning Test was particularly impressive.
This test is an excellent predictor of the ability of patients to return to normal
function."

......more....