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Biotech / Medical : ARIAD Pharmaceuticals -- Ignore unavailable to you. Want to Upgrade?

To: Mike McFarland who wrote (535)	4/25/1999 6:44:00 AM
From: Mike McFarland	Read Replies (2) \| Respond to of 4474

NFkB up-regulates expression of numerous cytokines including TNF, IL-1, IL-6, IL-8, VCAM, ICAM (references in this paper) stockton-press.co.uk I guess it's time to go back and see what Ariad mentioned in that PR from last fall... NF-kB plays a key role in regulating the human immune system. In B cells, it regulates the transcription of genes involved in the production of antibodies. NF-kB also regulates the transcription of many genes in activated T cells that play a major role in inflammatory and immune-related disease. Substances that inhibit NF-kB-mediated events may be useful for treating or preventing a number of immune-related or inflammatory disorders such as asthma, inflammatory bowel disease, multiple sclerosis and rheumatoid arthritis. NF-kB is also believed to play an important role in neurological disorders, such as Parkinson's disease and Alzheimer's disease. corporate-ir.net Okay okay, that horse is dead. I promised on the ntii thread I'd go away for a couple weeks...I really need to stop surfing the net so much! Good think I don't have a laptop, wont be able to spew urls on vacation;-)