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Biotech / Medical : Sepracor-Looks very promising -- Ignore unavailable to you. Want to Upgrade?

To: BMcV who wrote (2542)	4/27/1999 11:52:00 AM
From: j_fir2	Read Replies (2) \| Respond to of 10280

Mazen, did you get your position ironed out? Oops, a truly accidental pun that I'll let stand. I guess there was just one problem with our buy-up enthusianm a while back--SEPR and a lot of the techs had to take a hit first. I'm afraid our jollity and SEPR's cardiac will be forever linked in my mind--a shame, it was so much fun. I've got my SEPR tucked away in so many different places (lingerie chest, Tuck-it-Away Storage, between matresses and under the bed, in my grandmother's needlework box), that even if I'd had the wits/wherewithal/nerve to take advantage of the swings (what swings, you may ask? DIPS!), I really could only watch and commiserate. The market really makes one humble, doesn't it? I just HOPE that all my hard work (at other times) (and of course that of our other thread members, including your honorable self) will pay off handsomely down the road. And it may not be that far down the road. Near term, things seem to be looking up. Since I continue to watch and hold if not leap (oops, another pun), I am glad to see positive movement. Hope all is well. j'fir2

To: BMcV who wrote (2542)	4/27/1999 2:00:00 PM
From: Biomaven	Read Replies (1) \| Respond to of 10280

>>Sepracor's (R,R)-Formoterol Phase IIA Study Complete Not sure why they compared (R,R)formoterol to Ventolin (which is our old friend albuterol). The obvious comparison is of course to formoterol itself. However based on what I know about formoterol, the results looked good. Formoterol seems generally viewed as having a 12 hour effect, so improving this to 24 hours would certainly be significant. Formoterol is generally described as having a fairly quick onset of action, but I'm not sure I've ever seen it described as immediate. Formoterol typically has the same sort of side-effect profile as albuterol. Still fairly early, but this could be another significant drug for SEPR. On another topic, the ML bond/stock hybrid was interesting. Might be a good investment for an IRA for someone who needs to be down-side risk averse. Certainly an expression of confidence by ML in SEPR to include it with PFE and WLA. (BTW, these are the only 3 stocks involved, although the release seems to imply there are also others). Peter