SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?


To: Zebra 365 who wrote (21502)4/28/1999 11:55:00 PM
From: Cacaito  Read Replies (1) | Respond to of 23519
 
( BW)(TX-ENDOVASC)(ENDV) Endovasc Ltd. Inc. Announces
Confirming Evidence on PGE-1 in Preventing Heart Vessel Blockage;
Presented at Washington DC Meeting

Business Editors/Health & Medical Writers

MONTGOMERY, Texas--(BUSINESS WIRE)--April 28, 1999--Endovasc Ltd. Inc. (OTC
BB:ENDV) today announced that Baylor College of Medicine presented new data at the
Experimental Biology Meeting last week on the efficacy of Prostaglandin E-1 in inhibiting
the migration of vascular smooth muscle cell (thought to be the main cause of reblockage
of blood vessels) by disruption of stress fibers and adhesion plaques.
Prof. Charles Seidel's (Baylor's Section of Medicine - Cardiovascular Sciences) data
was further substantiated by Buerke and co-workers from Johannes
Gutenberg-University in Mainz, Germany. Their independent work confirmed (at the
same meeting) that Lipo-PGE-1 significantly reduced intima proliferation and smooth
muscle cell proliferation in the animal model.
"What this means," said company spokesman Dr. David P. Summers, "is that if this
effect continues to be maintained in the human model, then we have a home run product
within a $2 billion market. We should have early indications of its success in humans by
the beginning of the third quarter. If approval comes from the FDA quickly, we could
easily niche out $200 million from this market by the end of three years."

My comment: This is a basic science study (not in vivo humans yet). Few months ago there were some British? reports that Muse could help in the improving, delaying or even cure of certain ED cases, beyond just enhancing erections. This could be some of the basic mechanisms involved. Plus, the little prostaglandins escaping to the general circulation could improve the heart too (ok the last sentence is a little stretch).