To: Zebra 365 who wrote (21502 ) 4/28/1999 11:55:00 PM From: Cacaito Read Replies (1) | Respond to of 23519
( BW)(TX-ENDOVASC)(ENDV) Endovasc Ltd. Inc. Announces Confirming Evidence on PGE-1 in Preventing Heart Vessel Blockage; Presented at Washington DC Meeting Business Editors/Health & Medical Writers MONTGOMERY, Texas--(BUSINESS WIRE)--April 28, 1999--Endovasc Ltd. Inc. (OTC BB:ENDV) today announced that Baylor College of Medicine presented new data at the Experimental Biology Meeting last week on the efficacy of Prostaglandin E-1 in inhibiting the migration of vascular smooth muscle cell (thought to be the main cause of reblockage of blood vessels) by disruption of stress fibers and adhesion plaques. Prof. Charles Seidel's (Baylor's Section of Medicine - Cardiovascular Sciences) data was further substantiated by Buerke and co-workers from Johannes Gutenberg-University in Mainz, Germany. Their independent work confirmed (at the same meeting) that Lipo-PGE-1 significantly reduced intima proliferation and smooth muscle cell proliferation in the animal model. "What this means," said company spokesman Dr. David P. Summers, "is that if this effect continues to be maintained in the human model, then we have a home run product within a $2 billion market. We should have early indications of its success in humans by the beginning of the third quarter. If approval comes from the FDA quickly, we could easily niche out $200 million from this market by the end of three years." My comment: This is a basic science study (not in vivo humans yet). Few months ago there were some British? reports that Muse could help in the improving, delaying or even cure of certain ED cases, beyond just enhancing erections. This could be some of the basic mechanisms involved. Plus, the little prostaglandins escaping to the general circulation could improve the heart too (ok the last sentence is a little stretch).