Silicon Investor (SI) -- The First Internet Community

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Biotech / Medical : ATIS is on the move! -- Ignore unavailable to you. Want to Upgrade?

To: Rick Strange who wrote (1825)	5/6/1999 11:10:00 PM
From: Marshall Teitelbaum	Respond to of 2205

Rick, Of interest: foxnews.com This all could play out very well over the longer term. ATIS does a periodic "What's New?" update, but I don't know of a link. The update included: "Advanced Tissue Sciences Presents Cartilage Update On May 5, 1999, Advanced Tissue Sciences reported progress in its program on tissue-engineered cartilage. Ronda Schreiber, Ph.D., Program Manager of the Neocyte Joint Venture, presented an update on the Company's growth of human cartilage implants at the third annual Orthopedic Tissue Engineering meeting sponsored by the Institute for International Research. Dr. Schreiber's presentation, entitled "Tissue-Engineered Cartilage Implants for the Treatment of Cartilage Defects," described the Company's proprietary approach for growing human cartilage in vitro and success in engineering uniform articular cartilage implants up to two millimeters thick after multiple passages or expansions of human chondrocytes (cartilage producing cells). The importance of scaffold design and chemical composition, as well as the effect of the use of a hydrodynamic bioreactor culture system, were also discussed. In addition, a preclinical equine model, developed in conjunction with Wayne McIlwraith, B.V. Sc., Ph.D., and David Frisbie, D.V.M., M.S., Ph.D. Candidate, of Colorado States University, was presented. Tissue engineered equine cartilage constructs were implanted into low weight bearing full-thickness osteochondral defects along with various bone fillers. Arthroscopic examination confirmed that mature constructs remained in place, illustrating the utility of this large animal model. "Our progress in growing human cartilage with characteristics similar to those constructs which, in our earlier preclinical studies in a small animal model, were shown to enhance healing and integration brings us closer to the clinic," said Gail K. Naughton, Ph.D., President and Chief Operating Officer. "Our ongoing collaboration with Colorado State Univeristy will help to further test our product in an animal model which closely simulates the human setting." " The rest of the update simply goes over old news, referring to the 3/25 Transcyte cost-effectiveness data presentation, the 2/99 info. on recent developments in tissue-engineered vascular grafts, the 1/99 patent issuances(now over 49), and the recent articles and radio/television appearances. This all may already be available on the ATIS website...they were supposed to be updating it on Wednesday, but I haven't checked it yet this week. I agree about the need to keep it updated more regularly though., as presentations, etc. have been well behind. Meanwhile, the trading continues to be working on exactly where the new current support will be as volume slows. Should be lots at 3 3/4 if 4 doesn't hold, given the bump up from there the other day, although it would be nice if 4 held. We shall see. Talk to you. Marshall

To: Rick Strange who wrote (1825)	5/7/1999 9:44:00 PM
From: Marshall Teitelbaum	Respond to of 2205

Rick and all, Today's news: biz.yahoo.com Continues to be interesting, as this is good pr for the product in advance of it ever coming out. Focuses on the benefits of the human component to make it stick out above other similar products...etc. Also, fwiw, the rumor that was mentioned last week was now apparently meant for "next,", meaning that 5/12 would be the date. We shall see. If there is validity to it, I would expect to see a rise in volume over the next few days of trading. have a nice weekend all, Marshall