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Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: Mkilloran who wrote (7619)5/6/1999 10:36:00 AM
From: BigKNY3  Read Replies (1) | Respond to of 9523
 
MK: Thanks for the link. Message 9353391

It will be interesting to actually read the methodology and results of this study. Several questions that are obviously not addressed in the PR release are:

- Why were the results combined for both "Viagra failures" and "patients experiencing side effects with Viagra"? What was the efficacy rate within these two groups? The % of success in the Viagra failure group would be a particularly interesting % to know.

-Did the patient group that experienced side effects with Viagra include patients in which Viagra may have been effective but is contraindicated ie Nitrates? What was the success rate in this group?

-Was this a placebo controlled study or open label? What would have been the placebo effect in these groups?

-How were the patients selected?

-What was the side effect profile of the drugs used?

-Why did 35% of the patients chose to discontinue using the drugs used in the study? Were these patients responders or non-responders?

BigKNY3



To: Mkilloran who wrote (7619)5/7/1999 1:12:00 AM
From: BigKNY3  Read Replies (1) | Respond to of 9523
 
MK: Here is a link to the abstract on this study including toleration and side effect profile. Note the use of Actis in 34 patients. auanet.org.

The combination of the results from the "failure" group with the "side effect" group is probably masking mixed results from one of these groups. Certainly, these two patient groups are quite different.

BigKNY3