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Biotech / Medical : Sepracor-Looks very promising -- Ignore unavailable to you. Want to Upgrade?

To: j_fir2 who wrote (2879)	5/20/1999 3:09:00 PM
From: BMcV	Respond to of 10280

Just picked more LEAPS. Which raised a question in my mind: to what extent to option purchases deflect demand for the stock itself into derivatives? That is, if we're all buying options, who's buying the stock? And can the substitute demand be strong enough to weaken the stock?

To: j_fir2 who wrote (2879)	5/20/1999 10:05:00 PM
From: erin4	Read Replies (1) \| Respond to of 10280

As a psychiatrist I can assure you that Prozac is still the most widely prescribed antidepressant on the market. It is the second most prescribed medicine of all medicines in the USA. The next highest antidepressant is Zoloft (Pfizer) in fifth place for all meds in the US. Perhaps all the SEPR stockholders could use some Prozac secondary to the falling stock price.

To: j_fir2 who wrote (2879)	5/22/1999 11:10:00 AM
From: George Dawson	Read Replies (1) \| Respond to of 10280

I don't think the issue is necessarily if a new antidepressant will come along that is superior to Prozac. I can assure you that antidepressant trial results can be controversial and depending on the methodology used - some show negligible benefits over placebo. Clinical trials for the FDA use a fairly standard protocol. I mention this only because it would probably take a vastly superior antidepressant to demonstrate clear benefits over the others. One area that doesn't seem to be considered is the competition between a different isomer and fluoxetine (generic Prozac). If Prozac is widely prescribed and effective now and most people are not getting side effects that would cause them to stop taking it - that would seem to be formidable competition to the new isomer. George D.