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Biotech / Medical : Techniclone (TCLN) -- Ignore unavailable to you. Want to Upgrade?


To: Terry D. who wrote (3100)5/23/1999 1:35:00 PM
From: shero  Read Replies (1) | Respond to of 3702
 
Let me distract you with some facts. All this talk of Dr. Sturm made me decide to review some documents from my TCLN "due diligence" file. Actually its like the archives and takes up almost 1/2 a file cabinet drawer. Anyway, as Sergant Joe Friday says, "Just the facts"--drum roll...

"In collaboration with Drs. Stephen Sturm and Laura Thompson at the Brotman Medical Center, Culver City, Ca and Dr. Stan Mills at the Oklahoma Medical Center, a new therapeutic trial was initiated to test the clinical effectivness of TNT-1 in the treatment of patients with advanced prostate cancer. Under the sponsorship of the Patients Advocate for Advanced Cancer Treatment (PAACT), a physician's sponsored IND (#4111) was obtained to study the effects of weekly x3 doses of biotinylated TNT-1 (50mg/dose) followed 4 days later by 20 mCi of I-131 labeled streptavidan (2-5 mg/dose)."

It goes on and on so I won't. My info was from something made available to me copyrighted in 1993. here is the summary
1) rapid uptake of radiolabeled streptavidin in the bony metasases first seen a 5 hrs.
2) rapid clearance of blood pool seen at 24 hrs.
3) evidence of tumor destruction...
4) decreased bone pain in 3 patients
5) COMPLETE REMISSION (not my words) in one patient with PSA levels returning to near normal. (At the time of that report the patient had been in remission over 2 years) PSA went from 210 to 6.2 by day 240.

There you have it. And this study is 8 years old, so why should anyone (except the shareholders) be in a hurry now? Certainly cancer patients can wait! (heavy sarcism).