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Biotech / Medical : Pharmacyclics (PCYC)

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To: JMarcus who wrote (694)1/16/2004 3:45:53 PM
From: Icebrg  Read Replies (1) of 717
 
Marc

>>It just so happens that NSCLC metastasizing to the brain provides a unique opportunity to show demonstrable therapeutic benefits without extending the trial all the way out to the traditional endpoint of a survival benefit. Which isn't to say that the drug has no survival benefit. Quite the contrary. The endpoint of neurological progression is just faster and easier to prove.>>

If the drug works as expected this will no doubt be a relatively "fast and easy" way to approval. The reason traditional endpoints like survival or time to disease progression can not be used is that these patients, who are suffering from a systemic disease, may well die from other manifestations of the disease.

Erik
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