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Biotech / Medical : Lidak Pharm. [LDAKA]
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To: Red Dragon who wrote (801)1/5/1998 6:10:00 PM
From: Henry Volquardsen  Read Replies (1) of 1115
 
Red Dragon,

To save time I am including a link for a post I addressed to you back in September on the subject of the placebo

Message 2182057

And a link to your response to me

Message 2182191

So to summarize, at the FDA's request they tried to come with a placebo that appeared to the senses to be Lidakol while not being Lidakol. To do this they tried to take the Lidak formulation and deactivate it. They failed and that is why the placebo was active. It was not a case of mixing up 'vaseline and oil'. It was basically Lidakol. BTW technical point, neither Lidakol, the placebo or any other formulation cure herpes. They just reflief the suffering.

Your statement It's much more likely that the reason that Lidak and placebo show the same time to healing is that Lidak is ineffective. does not make sense. If Lidakol showed the same healing time as no treatment THAT would mean that Lidakol was ineffective. If Lidakol shows the same healing time as the placebo and both showed several days improvement over no treatment THAT would mean both ointments were effective.

Comparing 4-5 days of healing within the trial to 8-10 days that "untreated" lesions is not setting up a smoke screen. It is part of the normal analysis. Your comment that the 8-10 days "untreated" lesions take to heal could include immunocompromised patients (with HIV, etc.), among other confounding variables. is pure speculation and groundless. To suggest this was done is to suggest fraud.

Your suggestion that if Lidakol showed 4-5 days to heal and the placebo took roughly the same time that IF they had created a third arm of untreated lesions, this group would also show roughly 5 days to heal in this particular patient group. does not hold up. It is has been established by other researchers that untreated oral herpes lesions take 8-10 days to heal.

Henry
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