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Biotech / Medical : wla(warner lambert) -- Ignore unavailable to you. Want to Upgrade?


To: Bull-like who wrote (862)7/15/1999 6:00:00 PM
From: Anthony Wong  Respond to of 942
 
Dall, I don't think today's strength has anything to do with that article either. Possibly some pre-earnings bullishness, and the fact that Lipitor and Rezulin new prescription numbers remained quite healthy (read that in the labpuppy.com site a few days ago).



To: Bull-like who wrote (862)7/15/1999 6:19:00 PM
From: Anthony Wong  Respond to of 942
 
SG Cowen reiterates strong buy on WLA today, upbeat meeting with top analyst
(From Nordby.com)



To: Bull-like who wrote (862)7/15/1999 6:26:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 942
 
SmithKline's Avandia Prescriptions Top 11,000 a Week, NDC Says

Bloomberg News
July 14, 1999, 7:32 p.m. ET

SmithKline's Avandia Prescriptions Top 11,000 a Week, NDC Says

London, July 14 (Bloomberg) -- SmithKline Beecham Plc's
diabetes pill Avandia captured more than 11,200 new prescriptions
in the week ended Sunday, according to NDC Health Information
Services.

That gave Avandia, which won U.S. approval in May, about
2.6 percent of the market for new diabetes prescriptions, said
NDC's DirectRx Service, which tracks prescription sales at U.S.
pharmacies. The drug has had more than 45,000 new prescriptions
and refills since its June introduction, NDC said.

Avandia is part of a new class of diabetes pills that help
some people manage their disease without insulin shots. Avandia
is seen as a successor to a similar medicine, Rezulin. Rezulin is
a Sankyo Co. drug that Warner-Lambert Co. markets.

About 1.6 million people have tried Rezulin since the drug's
1997 introduction. In some cases, the drug worked where other
medicines had failed. That spurred demand for Rezulin. The drug's
sales rose 78 percent to $748 million in 1998.

Analysts have said 1998 sales likely will be the peak for
Rezulin, which has been linked to fatalities and cases of serious
liver damage. The FDA has several times added restrictions to the
drug's warning label.

Avandia and another Rezulin rival, Takeda Chemical
Industries Ltd.'s Actos, so far seem less likely to cause liver
damage than Rezulin is.

New prescriptions for Rezulin fell to about 29,450 in the
week ended Sunday from about 33,230 in the week ended May 2,
according to NDC. The drug's share of the new prescription market
fell to 6.8 percent from 7.8 percent.

Analysts expect the U.S. Food and Drug Administration to
approve Actos within the next week. Eli Lilly & Co., one of the
world's top-sellers of insulin, will help Takeda market Actos in
the U.S.



To: Bull-like who wrote (862)7/16/1999 6:17:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 942
 
FOOL ON THE HILL: Learning About Warner-Lambert
An Investment Opinion
by Warren Gump

July 16, 1999


Those of you have followed my writings probably know that I am quite fond of the biotechnology industry. With the innovations likely to emerge from this industry as genome research expands exponentially, I find few areas more attractive for long-term shareholders willing to endure stock price volatility inherent with companies working on revolutionary discoveries. Up to this point, most of my writing has been on pure-play biotech companies like Amgen (Nasdaq:AMGN - news), Biogen (Nasdaq:BGEN - news) , and Immunex (Nasdaq:IMNX - news) . But these firms aren't the only way to gain exposure to the industry. Traditional pharmaceutical companies are also quite involved in the sector.

What's the advantage of investing in one of the old-line drug companies over a full-fledged biotech operation? Primarily the fact that these companies have a broad base of existing products that generate growth and help finance R&D efforts. The major biotech companies only have one or two major products currently on the market, whereas most of the big pharmaceutical companies are selling many drugs. Given their sheer size, the traditional drug companies also have more money to invest in R&D. Pfizer (NYSE:PFE - news) and Merck (NYSE:MRK - news) each will spend well over $2 billion on R&D this year, whereas Amgen, the biggest biotech company, will invest $850 million. On the other hand, those dollars are invested over a wider array of efforts and any individual new product must be bigger to have a material impact on the larger pharmaceutical firms.

I find many of the big drug companies interesting. One that really catches my eye, though, is Warner-Lambert (NYSE:WLA - news) . Right now the company is achieving tremendous results with its Lipitor cholesterol drug and its aggressive move to expand its presence in the biotech arena. Earlier this year, the company issued stock worth $2.1 billion to acquire Agouron Pharmaceuticals, which uses genetic engineering extensively in its drug development process. Beyond its currently marketed Viracept protease inhibitor, Agouron has several drugs in its pipeline to help treat cancer and HIV/AIDS.

Before talking about the pharmaceutical side of Warner-Lambert, it is important to realize that the company has two other divisions. The consumer health care group sells products like Rolaids, Sudafed, Lubriderm, Benadryl, Listerine, and Schick shaving supplies. Last year, it achieved sales of $2.7 billion (27% of the company's total) and $510 million in income before taxes (24%). The confectionary business, marketers of items such as Chiclets, Dentyne, Certs, and Halls cough tablets sold $1.9 billion of products (18%) and earned $159 million before taxes (7%). These divisions have seen sales and earnings declines over the past two years, but they generate cash flow
that helps fund the company's other operations.

Pharmaceuticals account for the majority of Warner-Lambert's business. Last year, this division had sales of $5.6 billion (55%) and income before taxes of $1.5 billion (69%). The phenomenal success of Lipitor and Rezulin, a diabetes drug that has likely seen revenue peak, have fueled a doubling of sales and a tripling of profits in the pharmaceutical segment.

Rezulin had been a hot shot, with sales moving up 78% to $748 million from $420 million in 1997. With the recent introduction of an effective competitive product, however, Rezulin has been made a second-line defense. In isolated instances, Warner-Lambert's drug has been associated with severe liver problems (including deaths). Although that drug now faces declining sales, soaring sales of Lipitor, which is co-promoted with Pfizer, should more than offset that downturn. After doubling last year to $2.2 billion, the company expects Lipitor's sales to reach $3.3 billion this year and $4 billion in 2000.

The company has additional drugs experiencing substantial sales growth. Revenue from anticonvulsant Neurontin shot up 76% to $514 million, while antihypertensive Accupril enjoyed 20% sales growth to $454 million. Viracept, the protease inhibitor picked up in the Agouron acquisition, should also boost sales. Over the past 12 months, the drug had $500 million in revenue -- with the latest quarter's sales still growing 30% over the prior year.

Sustaining the company's growth is highly dependent on finding new therapies. If recent history is any indication, things are looking good. In the past year, Warner-Lambert began co-promoting Celexa, a depression treatment, with Forest Laboratories (AMEX:FRX - news) . Estimated sales for the year will be $300 million. The company also introduced a new antibiotic, Omnicef, which has been well received. To help ensure a healthy flow of new products, the Warner-Lambert is dramatically pumping up R&D spending. Current year expenditures for this line item are projected to rise 33% to $1.2 billion.

With pharmaceuticals comprising a major portion of the company's overall revenues, Warner-Lambert's margins are quite impressive -- although not as high as other pure pharmaceutical firms due to the consumer health and confectionary operations. Gross margins were 74%, up from 68% two years ago as the positive impact of Lipitor and other drugs took effect. For the same reason, the company's operating margin increased from 16% to 17%. With strong cash flow, the company's balance sheet is pretty clean. Although $1.5 billion in debt sits on the balance sheet, this is mostly offset by $1.2 billion in cash.

With such a powerful lineup under its belt, Warner-Lambert might be worth investigating to gain exposure to the drug/biotech sector. If you are interested in learning about the company, you might want to check out its website. (They don't yet have an obvious link to the Agouron site, which gives you information on their novel drug discovery process.)

One nice aspect of Warner-Lambert is its investor-friendly dividend reinvestment program. In addition to allowing optional cash payments, you can avoid a broker altogether and purchase your first shares directly from the company for a $15 fee (the minimum initial investment is $250).

fnews.yahoo.com