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To: Bill Harmond who wrote (102983)	5/8/2000 8:43:00 PM
From: allen menglin chen	Respond to of 164684

Monday, 8 May, 2000, 16:45 GMT 17:45 UK Complete human gene map claimed news.bbc.co.uk Raw data from chromosome 21 By BBC News Online science editor Dr David Whitehouse A "dark horse" private company in the US is claiming to have won the race to produce a complete gene map of humans. At the same time publicly-funded scientists in Germany and Japan have passed another milestone in decoding human chromosome 21. The private company Doubletwist is a relative newcomer in the genome race and claim to have obtained the first "working draft" of the entire human genome. They say they did this by analysing publicly-available data using Sun workstation computers. The company believes its rough draft comprises the 105,000 genes of the human genetic blueprint. Surprise entry "The Human Genome Project has done a tremendous job of providing the primary sequence of more than 80% of the genome to date. We have built upon this accomplishment by processing this data to reveal its most important information - the genes," said John Couch, Chairman and CEO of DoubleTwist. Doubletwist's entry into the genome race comes as a surprise to genetic onlookers as it was thought that the race to complete the human genome was between the privately-funded Celera Genomics corporation and the publicly-funded Human Genome Project (HGP). Three weeks ago, Celera's CEO Craig Venter announced that his company had obtained the entire gene sequence of a human but had not yet assembled it into the correct order. He added that it would only take them a few weeks to complete that task. Sequencing landmark The decoding of chromosome 21 is a significant achievement for the HGP. It will be published in the journal Nature. It comes as rumours circulate in the scientific community that an official announcement that the entire human genetic blueprint has been sequenced is just days away. The announcement could be made at an important gathering of genome scientists on Thursday at Cold Spring Harbour Laboratory, Long Island, US. Chromosome 21 is the smallest human chromosome comprising less than 1.5% of the entire human genetic code. Extra copies of the chromosome result in Down's Syndrome, the most frequent cause of mental retardation. It affects one in 700 births. The scientists say that chromosome 21 has 33,546,361 base pairs of DNA arranged into 127 genes.

To: Bill Harmond who wrote (102983)	5/8/2000 9:05:00 PM
From: GST	Respond to of 164684

Bought CA at 45 1/2.

To: Bill Harmond who wrote (102983)	5/8/2000 9:28:00 PM
From: Robert Rose	Read Replies (1) \| Respond to of 164684

Great article, William. I wish it mentioned the author....

To: Bill Harmond who wrote (102983)	5/8/2000 10:22:00 PM
From: Victor Lazlo	Read Replies (1) \| Respond to of 164684

<<Not only has its invincibility been shattered, but also more than $200 billion of its market value has evaporated into the vaporsphere. >> Actually, no, it has not "evaporated into the vaporsphere. " It has been sold and the cash pocketed. Only an idiot would believe that it "evaporated." jeeez. Such inane drivel.

To: Bill Harmond who wrote (102983)	5/9/2000 10:28:00 AM
From: H James Morris	Read Replies (1) \| Respond to of 164684

William, are you sure Double click is a superbly managed company?;-) > New York, New York, May 8, (Bloomberg) -- DoubleClick Inc. mistakenly placed ads for Brown-Forman Corp.'s Jack Daniel's whiskey and Southern Comfort liquor on the Comics.com and Snoopy.com Web sites, the Wall Street Journal reported. An official for DoubleClick, which was hired by Brown-Forman to place banner ads on Web sites that would reach its typical drinker, said it was a ``mistake'' that resulted from a clerical worker entering the wrong information on an ad-placement form. A spokeswoman for United Media, which owns Comics.com, said the company's contract with DoubleClick prohibits any alcohol, tobacco or pornographic content on its sites, and it notified DoubleClick immediately when it noticed the ads, the paper said. DoubleClick is under investigation by the U.S. Federal Trade Commission for its method of tracking the online movements of Internet users. (WSJ 5/8 B1)