To: XenaLives who wrote (2745 ) 1/31/2001 3:36:09 PM From: NeuroInvestment Read Replies (1) | Respond to of 52153 I know nothing about charts and consider them primarily a vehicle for self-fulfilling prophecies. But I do know a fair amount about NEOT. You have two opposing forces which account for the volume and lack of price movement: 1) The rodent data indicating Neotrofin triggers stem cell proliferation hits a hot button, stem cell access and modulation. It may explain (partly) a mechanism of action that thus far had been vaguely defined. It is also a reminder that, in spite of its mismanaged Phase III effort in 2000, which had to be scuttled when the dosing turned out to be wrong, Neotrofin is still ahead of the regenerative therapies group as a potential tx for AD. It lags behind memantine as the first non-cholinesterase drug, but memantine has protective effects, not regenerative. vs. 2) NEOT has burned too many public relations bridges with impulsive anecdotal claims regarding clinical effects and Big Pharma interest. The announcement last fall that Neotrofin was being 'fast-forwarded', when explaining that the large-scale Ph III was being terminated, was the piece de resistance, or for skeptics, the coup de grace. Thus announcements from NEOT that might stir more sustained interest in another company will be taken with much salt. Furthermore, they need money, and the likelihood of dilution under onerous terms looms large. So: #1 brought the stock price from 2.25 to 2.70 or so, #2 keeps it from going beyond. An oversimplified explanation that doubtless leaves out all sorts of nefarious manipulation, short maneuvering, and such, but I prefer to keep it simple. NeuroInvestment (www.neuroinvestment.com)