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Biotech / Medical : RNAi -- Ignore unavailable to you. Want to Upgrade?


To: tuck who wrote (102)9/18/2003 5:31:19 PM
From: SemiBull  Read Replies (1) | Respond to of 671
 
Comprehensive interference

RNAi-sensitive Drosophila cells provide insights into lamella formation and motor protein specificity | By David Secko

biomedcentral.com



To: tuck who wrote (102)9/20/2003 9:34:12 AM
From: nigel bates  Respond to of 671
 
Drug Discovery & Development

Very interesting article. Clearly it's a little too early to get wildly excited about therapeutic use -
Usman expects his company to file an IND with an RNAi-based drug by early 2005
- and that's from a company with experience of producing RNA for in vivo delivery... and it may well not work first time out...and the number of addressable disease targets seems limited.
Compared with (say) fully human mABs, which ostensibly present fewer development problems, and looking at how long it's taken companies like ABGX and MEDX to start realising their potential, I suspect it will make sense to sit on the sidelines for some time yet.

OTOH, LEXG must hate this stuff.