To: Lazarus_Long who wrote (279 ) 1/19/2005 10:00:01 AM From: fresc Respond to of 42652 AHH LAZ! I am sure there is many:)) What's this?????????/ CTV.ca News Staff Imagine preventing cancer with a vaccine. It's still a few years away but researchers say they are getting closer. And some key research is happening right here in Canada. Researchers are racing to develop vaccines that will train the immune system to marshal the body's own natural defences to rid the body of cancer. At Montreal's Jewish General Hospital, they're custom designing a cancer vaccine. They're taking immune cells from the patients and mixing them with bits of the patient's tumour so the immune system can learn to seek out and destroy circulating cancer cells. "We would like to get their immune system to react against the kidney tumour," explains Dr. Gerald Batist. "If it goes after the tumour cells, it will go after cancer wherever it is in the body." Doctors have so far treated only a handful of patients using this approach. There's no hard data yet but the signs are encouraging. The same goes for the some 200 other cancer vaccines in the research pipeline. "This is a very dynamic area of science," says Dr. Neil Berinstein of Aventis Pasteur. Berinstein and his team are working on vaccines for skin and colon cancer using a different approach. Normally, killer immune cells don't recognize tumour cells and can't attack them. So doctors inject cells that have been altered to signal those killer cells to recognize and lock onto cancer cells, killing the tumour. "Because it works by an entirely different mechanism and has little or no side effects, we believe that we will be able to combine it with certain standard therapies, such as chemo, and perhaps reduce the number of doses of chemo or reduce the number of drugs of chemo." But there remains many unanswered questions. Doctors still have to confirm the vaccines are safe, and whether one vaccine will work for many patients or if each vaccine has to be custom designed from the patient's own tumour. "We are going to learn something from this trial. Even if we don't cure these patients, we are going to learn what we are not doing right so we can improve and come back again." Vaccine therapy for prostate cancer could be approved within a year, giving doctors and patients the first new approach to cancer in decades. Next topic, Laz! ( If these vaccines do make it to market,I bet the will be reasonably priced so all can afford).