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Biotech / Medical : Agouron Pharmaceuticals (AGPH) -- Ignore unavailable to you. Want to Upgrade?


To: Oliver & Co who wrote (2694)11/8/1997 10:29:00 AM
From: JOHN W.  Read Replies (3) | Respond to of 6136
 
<Best adherence is when regimens are kept as simple as possible, with as few pills as possible.>

Is it still true that 18 pills a day are required with the new formulation.
If so, is it 6 pills three times a day, or 3 six times a day, etc?



To: Oliver & Co who wrote (2694)11/8/1997 2:23:00 PM
From: Oliver & Co  Respond to of 6136
 
I forgot to say that you Saquinavir can be used in combination with
several other drugs like Ritonavir(Norvir), Delavirdine(Rescriptor),
Nelfinavir (Viracept), and now with 141.

There will be a study published in the near future, PROA2001
141W94 + other PIs

Dose Group 141w94 Other PI
A 800 MG TID SQVSGV 800 MG TID
B SAME IDV 800 MG TID
C SAME NELF 750 MG TID
D SAME CANT REMEMBER
They have all showed huge drops in viral loads, almost 4 logs,
down to less than 20 copies.

CNS penetration, 12/13 patients treated with only RIT/SQV had
no detectable virus in CSF while on therapy.

JLL