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Biotech / Medical : Caprius(CAPR), Breast MRI(former ANMR/MAMO) -- Ignore unavailable to you. Want to Upgrade?

To: James L. Fleckenstein who wrote (2119)	11/11/1997 10:25:00 AM
From: luis a. garcia	Respond to of 2615

Excellent Dc Fleckenstein you are a stud. Very good description of the process. I think Dc Rhoden scans were in the average of twenty minutes?? Any two pass technique is heavily dependent on solving doc Yitre's problem...of fixing the breasts..in situ. Hence the Warren's cup technique. Question if rate of enhancement which I forget which university was doing a lot of work with is the key element in the discrimination of malingnancies and a sequence is obviously required to develop the rate of abpsorption curves then is the role of the fat supression overstated? luis

To: James L. Fleckenstein who wrote (2119)	11/11/1997 10:52:00 AM
From: Zeev Hed	Read Replies (1) \| Respond to of 2615

James, thanks for explaining the "new Art" of NMR and MAMO, so I understand from your description that a series of images is taken sequentially as the Gd is being injected (5 sec is an aweful small time interval for distribution in in venules and arterioles, when using iodine as a contrast agent for cardiovascular imaging in CAT I thought they waited minutes or more, maybe I should recheck my textbooks on this). How long would you estimate it takes to take a full mamogram? and do they do both breasts in the same field (or the same "take") Zeev

To: James L. Fleckenstein who wrote (2119)	11/14/1997 12:16:00 AM
From: luis a. garcia	Read Replies (1) \| Respond to of 2615

Dc Fleckenstein let me dispense with one issue which is been bugging me about fat supression ... OBTW this is CAPR or Caprius thread now a continuation of the ANMR...thread.. The issue of the 75 HZ difference in the resonance frequency of homogeneous fat from homogeneous water at a magnetic field strength of 0.5T .. i.e.: It would be nearly physically impossible to discriminate real time using hardware as in a heterodyne set saw filter or mixer etc. However the technique becomes realizable once you have it accurately Fourier Transformed into phase and frequency. This is oversimplifying the problem a bit. Because of the artifacts and secondary effects of the system both patient and machine and the differences machine to machine and magnet to magnet.. Therefore it becomes a problem of technique and finesse and yes a higher Field i.e. higher difference makes the secondary effects smaller and less troublesome in comparison. I really believe that with todays technology and a little tweaking and a lot of brain power you can develop reliable fat suppression technique. A very interesting problem and it can spin off additional patents as the special magnets that ANMR has developed recently and power suppliers etc... No doubt the science of builduing good MRi systems is different from wireless telephones in that it depends heavily in signal processing in software as opposed to hardware. At the next post dealing with fat suppression I will explore the special technique patented by Advanced Mammography... aren't you all happy about that pudding breath... luis