We have been able to scale up production of the two different ligands under potential clinical development consideration for VZV shingles treatment to approximately 200g scale already. We anticipate being able to scale up to approximately 500g level or more, as necessary. The process of chemically covalently connecting the ligands to the polymer backbone, to produce the nanoviricides, is now being investigated further to optimize the operations for scalability. At present, we have been able to make research quantities of the anti-VZV nanoviricides at approximately 10~20g scale in a reproducible manner. We are working on scaling up this last step of synthesis of a HerpeCide program drug candidate.