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Biotech / Medical : ArQule -- Ignore unavailable to you. Want to Upgrade?


To: ahhaha who wrote (173)2/5/1998 10:27:00 AM
From: Peter Silsbee  Read Replies (1) | Respond to of 399
 
>> What are the criteria of "promising"?

Ask the folks whose job is is to screen the libraries. I suspect they have some ideas on the subject.

>> Promising is heuristic and your assertion begs the question.

Heuristics have their uses. If we knew how to solve every problem from nothing but theory, then I would agree with you about ARQL's methods, and drug companies would have no use for ARQL's services. But we don't, I don't, and they do.

>> I don't see where the SBD group constrains the blowup. Indeed, it enters its own factor, j, into the equation, (j + m + k)^n, or j*(m + k)^n.

No, just the opposite. j dimensions of the search space are fixed, or at least relatively constrained, by any "thoughtful" design process.

What do the theoreticians say about practicality?

Lots of things, I'm sure. What did you have in mind?

PLS