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Biotech / Medical : Ionis Pharmaceuticals (IONS) -- Ignore unavailable to you. Want to Upgrade?

To: SnowShredder who wrote (1904)	4/8/1998 11:44:00 PM
From: Miljenko Zuanic	Read Replies (1) \| Respond to of 4676

Where'd...: Fist I though that your crap is not worth any respond. Than, my character is not to be short toward anyone, so why should you be excluded. >>PS: Better to remain silent than remove all doubt.<< My little scientist friend, where you are today I was long time ago. So you can put your science crap you know where. Also, I never claimed being bio-scientist, only organic chemist. And, dam good one. If you don't believe me, ask Dr. Olah at USC. Also, you can say halo in my name, it will be password to you. I will suggest that you take your nose up (or whatever you are doing now), buy flowers and candies, and visit few cancer patients. But, remove filters from eyes and brains. Be human. Talk to oncologist. Maybe you will learn that cancer is unpredictable, very adaptive, chronic diseases which love to fight back. Saying this, it is not to be pessimistic or optimistic. It is to be objective and realistic. Seams you like genomic and genetic, with opinion that there are answers to everything. Live in dreams. Regards yours two examples, Onyx's E1B vector is crapshot. It will hardly work. Destroying p53-cells (if at all and for cancer not of big importance) is note some as deploying p53 gene (Schering approach). Also, MOGN MGI 114 is crapshot. It continue to be a nice poison. Was and will remain, imo. Do you know how many rats survive drug, regardless the effects on tumor mass. Do you know what is damage to other organs? I guess not! Yes, I do follow cancer field very closely, clinical and science development. Definitely, you are the last persons with hum I may discuss this issue. Regards the science progress, after 50 years of fighting infectious diseases, we are still where we started, and will hardly move in future. We are still generating more diseases than we are able to cure. But, this may be against your scientific nature. We may win first round, but cancer and other diseases will return. This is not future prediction, it is from history. Agree that in next 10-20 years many new and better drugs and therapies will be developed, but as I stated early and so many times, only chosen COMBINATIONS (related to cancer type and patient nature) will be curative and successful. Very effective monotherapy in next 10 years, not likely. >>I hope that this enlightens you.<< No, not at all. Actually depressed me. Where are new generation heading? mz PS: Congratulation to ISIP on first NDA.