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Biotech / Medical : Ligand (LGND) Breakout! -- Ignore unavailable to you. Want to Upgrade?

To: squetch who wrote (19425)	4/22/1998 5:36:00 PM
From: Henry Niman	Respond to of 32384

I would think that LG268 is LGD1268. I'm not sure about LG100153. I did a quick Medline search and found two abstracts that refer to LG100153 as an RXR selective ligand, so I would guess that it's LGD1324 because that is LGND's other RXR selective ligand (in addition to LGD1268 and Targretin).

To: squetch who wrote (19425)	4/22/1998 5:38:00 PM
From: Henry Niman	Read Replies (2) \| Respond to of 32384

Here's what ABC had to say about recent cancer deaths: By Jenifer Joseph ABCNEWS.com April 21 - If a Titanic were to sink every day for five straight years, killing 1,500 passengers each time, wouldn't we sit up and take notice? Wouldn't we urge Congress to do more about it, to figure out what was making this happen? Well, that many Americans really are dying every day, but from cancer, not from ill-fated collisions with icebergs, according to new statistics released today. Cancer researchers found that the equivalent of 12 jumbo jets full of Americans die every week from lung cancer alone. These comparisons may be a bit on the melodramatic side, but as study author Dr. Vivienne Chen notes, the figures must be put into perspective so people will realize how widespread the disease really is. Chen is director of the Lousiana Tumor Registry at Louisiana State University. "We've become blind to the problem and complacent about taking better care of ourselves," says Chen. "If, for instance, we could get rid of smoking, we could get rid of 90 percent of all those lung cancer deaths-that would save 700,000 people." Canadian Cousins Similar The North American Association of Central Cancer Registries study, which accumulated data from 1990 to 1994, found that the incidence of cancer in Canada was similar to that of the United States. That's not surprising, considering that the general health status of the two countries is so similar. Among the study's other findings: Black men had a 20 percent higher rate of cancer than white men; but white women had a five percent higher rate than black women. The top three cancers in children were leukemia, central nervous system tumors and lymphomas. Although the new analysis didn't turn up any big cancer data surprises, Chen says many of her colleagues worry that it shows we aren't putting our government funds in the right place. We spend $3 billion each year to install air bags in new cars, in hopes of saving 300 lives a year. Meanwhile, cancer kills 2.6 million Americans a year, and the federally funded research budget is maybe twice that amount. "We need to get a message to our government, health officials and the public," says Chen. "We need more research if we ever want to reduce these deaths."