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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ) -- Ignore unavailable to you. Want to Upgrade?

To: John W. Andrews who wrote (13213)	8/13/1998 1:45:00 PM
From: VLAD	Read Replies (2) \| Respond to of 23519

pizza, In a nut shell. Vascular forms of ED are due to the destruction of the calcium pumps which allow blood to adequately flow to the penis. They are able to genetically produce these pumps via human DNA ie the pumps are produced by copying their blueprint for production off the appropriate human DNA. These pumps were then injected into the peni of aged impotent rats. When the rats were anesthetized and the penis was stimulated electrically, the rats were able to achieve erections for up to 75 days. So this was human "pumps" which were injected into rat peni. If it works on rats there is no reason to believe that it would not work on humans. This news is significant. If men with vascular impotence can be cured by going to the doctor's office 6 times a year for a shot then they certainly will not want to use Viagra nor MUSe given this choice.

To: John W. Andrews who wrote (13213)	8/13/1998 2:14:00 PM
From: AlienTech	Respond to of 23519

>>I read the abstract..but I'm just a pizzaman..in laymans terms can you give me the reader's digest on this one..<< That you dont necessarely have to be alive or awake to DOIT. I hear a lot of women find this problem with their husbands, long day at the office, all they want to do it sleep.. We now they dont even have to co-operate.. Take the needle and zap..

To: John W. Andrews who wrote (13213)	8/13/1998 4:55:00 PM
From: DaiS	Read Replies (5) \| Respond to of 23519

John, These two posts give what I know about the gene therapy work Message 5319236 Message 5416846 I would not get too excited about a gene therapy press release and its effect on share price - as people have noted we knew about the gene therapy at the CC. HOWEVER big splashes for research advances seem always to come when a paper is published, this happens with Nature or Lancet articles. ((To authors, the work is in the bag when they get acceptance - May in this case - but evidently authors are wary about shooting their mouths off until publication.)) Thus I guess Vivus, if they do plan a big event, would wait until the official publication date. Presumably gene therapy for ED is not as exciting as curing cancer in rats. But it looks like ED is a good candidate for gene therapy which generally has promised a lot but not delivered too much yet for a variety of technical problems for other illnesses. But just to repeat, it could be that the Vivus work is a winner - the paper looks good. Whatever criticisms we have of Vivus management, they appear to have latched on to the best group in the world in this area to do this work with. Vlad, I can try to find out about the Journal, as with other periodicals the August issue might be out in September if they have a backlog of accepted articles to publish, or could be earlier, in June - depends. DaiS