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To: david cameron who wrote (6689)12/30/1998 9:16:00 AM
From: John Hensley  Read Replies (2) | Respond to of 8359
 
News:

HENDERSON, Nev.--(BUSINESS WIRE)--Dec. 30, 1998--

Deal Brings the Largest Cool-Season Turfgrass and Forage Seed
Company Together with Kimeragen's Precise Genetic Modification
Technology to Develop New Turf and Forage Varieties

Kimeragen Inc. and AgriBioTech Inc. (Nasdaq NM:ABTX.O) (ABT)
Wednesday announced that they have entered into an exclusive
collaboration to develop turfgrass and forage seed products using
Kimeragen's enabling technology platform, "chimeraplasty," that allows
for the development of improved varieties with new desirable traits.
Chimeraplasty is referred to as "precise genetic surgery" because
specific genes are selectively modified without affecting the rest of
the genome or altering normal protein expression and cell function.
Kimeragen's enabling technology platform, chimeraplasty, allows
specific repair or replacement of small segments of genes.
Chimeraplasty is applicable to plants, animals, bacteria and human
cells. When used in clinical applications, this molecule is packaged
with a delivery system and then is administered into the subject and
ultimately the chimeraplast binds selectively to the portion of the
target gene to be modified.
Once bound, chimeraplasty activates the recipient's own
gene-correcting mechanism, which mediates the gene change. For plants,
the chimeraplast enters a plant cell, makes the desired genetic
change, and the modified cell is then grown into a full plant that
contains the new trait, which is passed to the next generation through
the seed.
ABT will have exclusive rights to Kimeragen's technology for all
forage and turfgrass species, subject to two prior non-exclusive
licenses. Earlier, ABT announced acquiring a research license to
"whiskers" transformation technology from Garst Seed Co.
(Advanta), an agreement that gives the company, at its option, the
opportunity to acquire a commercialization license for products
developed with this technology. The whiskers technology can be used to
deliver "chimeraplasts" into target plant cells.
"This new Kimeragen technology, which can be used to selectively
inactivate genes or to introduce targeted mutations to alter gene
function, provides us with an additional and important tool for
developing new products with unique and valuable traits," said Dr. Tom
Rice, ABT vice president, director of research, "and it expands and
strengthens our biotechnology capabilities and options."
"We are pleased that the largest cool-season turfgrass and forage
seed company will be applying our unique and proprietary technology in
their seed sector," said Gerald L. Messerschmidt, M.D., president and
chief executive officer of Kimeragen. "We look forward to working with
ABT to develop important new products in this area so that turfgrass
and forage seed users can enjoy the benefits of our highly selective
technology for introducing targeted genetic changes."
Kimeragen, a privately held company with headquarters in Newtown,
Pa., is engaged in the discovery, development and marketing of unique
products for human health, plant and animal/veterinary applications.
The company is developing chimeraplasty as an enabling technology
for three distinct business areas: pharmaceuticals to repair genetic
abnormalities implicated in a broad array of human diseases; plants
and industrial products to enhance genetic traits in plants; genomic
and transgenic animal technologies aimed at developing higher value
applications and products for human health and veterinary care.
Kimeragen plans to commercialize many of those applications
through partnerships with global leaders in these fields.
AgriBioTech is a fully integrated full service seed company
specializing in the forage and turfgrass seed sector, complete with
research and development of proprietary seed varieties, seed
processing plants, and a national and international distribution and
sales network.
The company has completed 33 acquisitions since Jan. 1, 1995 and
is the largest forage and cool-season turfgrass seed company in the
world, with a current level of annualized net sales of approximately
$475 million, including the previously announced pending acquisitions
of the alfalfa business and international sorghum units of AgriPro
Seeds Inc., Moore Seed Processors and Production Plus+, which have
annualized net sales aggregating approximately $35 million.
The statements discussed in this news release include
forward-looking statements that involve a number of risks and
uncertainties. These include AgriBioTech's historical lack of
profitability, need to manage its growth, intense competition in the
seed industry, seasonality of quarterly results, weather conditions,
volatile stock price and other risks detailed from time to time in the
company's Securities and Exchange Commission reports.