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Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: JEB who wrote (6594)1/1/1999 10:57:00 AM
From: BigKNY3  Respond to of 9523
 
Peabody Daily Log: December 31,1998

PFE Weekly Highlights:

- Highest daily PFE close of 126.13 reached on Thursday.
- All-time PFE High of 128.94 reached on Friday
- Highest weekly PFE close of 125.00 reached on Friday
- New pending Peabody Peak of 128.94 reached on Friday

PFE Versus the Dow:

........................PFE.....Dow ....Peabody Comments
Growth: since 1/1/98:......+67.6%...+16.1%....Another great year > 60%
Growth: week of 12/28/98:.+4.7%.....-0.2%.... Forbes & Celebrex
Growth: December 1998:..+11.7%.....+0.7%.....The Big Pharma/Celebrex divergence
Growth: 4th Quarter 1998:.+18.2%...+16.5%....Matches market
Growth: since 8/31/98:......+34.4%...+21.8%....Buy at Valleys!

-Click here for a 5 day comparison among PFE, MRK and the Dow.
The Cox-II Wars Scoreboard

quicken.com

Click here for a 5 year comparison among PFE, WLA and the Dow.
PFE has taking the lead.

quicken.com

Click here for a 5 year comparison among PFE, SGP and the Dow.
PFE has taken the lead.

quicken.com

Have a PFun New Year's Day!

BigKNY3

_________________________________________

The Peabody Log

Key: Peabody Peak (Intermediate High)
Peabody Valley (Intermediate Low)
___________________________________________________
PFE PFE PFE
Date Volume High/Ask Low/Bid Close Milestones
12/29/97 1,395,600 74 72 5/8 73 11/16
12/30/97 1,842,900 75 7/8 74 75 5/8 Dow +236
12/31/97 1,616,400 76 1/4 74 1/8 74 3/4 1997 Close
01/02/98 1,521,000 75 3/4 74 75 11/16
01/05/98 4,528,300 79 15/16 76 79 1/2 Peabody Peak
01/06/98 2,891,800 79 7/16 77 1/8 77 7/16
01/07/98 2,213,500 78 1/8 76 3/16 78 1/8
01/08/98 3,324,600 79 3/8 77 3/16 77 11/16
01/09/98 3,979,000 77 3/8 72 74 1/16 -6% swing intraday
01/12/98 3,836,400 77 71 1/16 76 7/16 Peabody Valley
01/13/98 2,904,400 78 77 77 5/16
01/14/98 2,547,300 78 76 9/16 77 13/16
01/15/98 2,786,200 77 7/16 75 5/8 75 3/4
01/16/98 3,746,100 77 75 5/8 77
01/20/98 4,944,600 80 7/8 78 80 7/8
01/21/98 3,749,000 80 1/4 78 1/2 78 15/16 Big Pharma Merger Mania
01/22/98 2,506,100 79 5/8 78 3/16 78 5/8
1/23/98 2,741,300 78 3/4 76 5/8 78 1/16
01/26/98 2,304,900 79 77 1/2 77 3/4
01/27/98 2,827,100 79 11/16 77 7/8 78 3/4
01/28/98 3,834,600 81 79 7/16 79 13/16 Last<80 day
01/29/98 3,323,300 82 7/16 80 1/4 81 1/2
01/30/98 2,285,600 82 1/8 80 3/4 81 3/4
02/02/98 4,297,100 85 1/16 82 3/8 82 5/8
02/03/98 3,041,900 82 7/8 81 9/16 82 9/16
02/04/98 2,260,700 82 1/4 81 81
02/05/98 2,892,200 82 5/16 79 5/8 79 3/4
02/06/98 2,306,200 81 3/8 79 15/16 81
02/09/98 2,356,700 81 13/16 80 3/16 80 7/8
02/10/98 3,616,800 83 15/16 81 7/16 83 13/16
02/11/98 3,065,500 84 3/8 81 7/16 83 11/16
02/12/98 2,476,300 84 15/16 82 1/4 84 7/16
02/13/98 1,962,200 84 3/16 83 3/8 83 5/8
02/16/98 President's Day
02/17/98 2,384,700 84 13/16 84 1/16 84 1/2
02/18/98 3,287,600 86 1/2 84 11/16 86 1/4 Celebra agreement
02/19/98 2,982,500 88 1/4 86 86 1/8
02/20/98 2,736,400 87 3/4 86 3/16 87 5/16
02/23/98 2,964,600 89 3/8 87 15/16 89 3/8
02/24/98 5,464,900 88 86 1/4 87 1/2
02/25/98 2,508,700 89 9/16 88 1/8 88 3/8
02/26/98 2,879,000 90 1/4 88 3/8 89 15/16 Possible MTG sale
02/27/98 4,198,900 91 7/16 87 7/8 88 1/2 Peabody Peak
03/02/98 2,713,200 89 3/16 87 9/16 87 13/16
03/03/98 2,749,900 87 1/4 85 5/8 87
03/04/98 3,353,300 86 1/4 84 1/2 85
03/05/98 2,716,700 86 3/8 85 85 1/2
03/06/98 4,073,900 86 1/2 84 1/8 86 1/4 Peabody Valley
03/09/98 3,045,600 87 7/16 86 86 7/8
03/10/98 3,151,100 88 5/16 86 9/16 87 7/8
03/11/98 2,884,400 89 1/16 87 3/8 87 1/2
03/12/98 2,188,100 87 7/8 85 15/16 86 1/16
03/13/98 2,602,500 87 1/8 85 13/16 86
03/16/98 3,076,200 88 3/8 86 9/16 88
03/17/98 3,224,600 89 15/16 88 9/16 89 3/8
03/18/98 2,947,900 89 7/8 88 88 1/4
03/19/98 5,683,600 90 3/4 89 90 WSJ article on Viagra
03/20/98 7,463,500 92 13/16 90 1/16 92 1/4 20/20 Viagra Broadcast
03/23/98 8,343,500 97 1/2 95 1/2 96 1/4
03/24/98 5,356,900 96 1/2 94 1/2 95 5/16
03/25/98 5,733,600 96 1/8 92 1/2 94 1/2
03/26/98 3,544,100 95 3/8 93 5/8 94 5/8
03/27/98 7,525,600 97 1/8 93 3/8 95 1/2 Viagra Approval
03/30/98 7,353,000 98 96 5/8 97 7/8
03/31/98 5,936,300 99 7/8 98 3/8 99 7/8
04/01/98 5,571,900 100 3/8 98 1/4 98 5/8 100 level broken
04/02/98 3,926,800 100 98 15/16 99 1/2
04/03/98 4,165,300 101 3/4 99 11/16 101 11/16
04/06/98 4,869,100 103 3/4 102 1/4 103 1/4 Peabody Peak
04/07/98 4,623,900 103 1/4 99 1/8 100 9/16 Viagra in pharmacies
04/08/98 4,361,600 101 1/2 97 13/16 98 15/16
04/09/98 3,677,700 99 13/16 98 99 1/4
04/10/98 Good Friday
04/13/98 3,135,100 101 1/16 99 9/16 101
04/14/98 3,083,800 101 1/16 98 1/2 99 1/16 PFE 1st Qt EPS
04/15/98 4,874,800 99 11/16 96 3/8 97 1/2
04/16/98 6,790,300 101 1/8 95 5/16 100 5/8 Peabody Valley
04/17/98 7,448,200 106 1/2 100 5/16 105 1/8 High Viagra Rxs forecasted
04/20/98 10,029,000 113 3/4 109 113 3/8 36M Viagra New Rxs
04/21/98 13,707,300 121 3/4 115 116 1/8 High for 1998
04/22/98 10,775,600 117 7/8 111 5/16 114 7/16
04/23/98 7,198,600 116 15/16 113 13/16 115 1/2 Annual meeting
04/24/98 8,321,900 118 1/2 116 1/2 118 Merrill ups EPS/High close
04/27/98 11,935,500 116 7/16 110 9/16 113 7/16 113M Viagra New Rxs
04/28/98 7,603,300 116 1/2 112 1/2 113 1/8
04/29/98 5,646,500 113 7/16 111 112 5/8 First Boston Downgrade
04/30/98 7,464,200 114 3/8 109 3/8 114
05/01/98 4,880,100 115 3/8 111 3/4 112 11/16 Smith Barney ups target
05/04/98 4,863,200 114 1/2 112 3/8 112 5/8 207M Viagra Rxs
05/05/98 5,882,900 112 3/4 109 3/4 111 11/16 AAO V vision
05/06/98 4,292,100 112 3/4 108 11/16 108 3/4
05/07/98 5,328,000 110 104 3/4 106 15/16
05/08/98 4,392,900 111 3/8 107 1/2 111 3/16 Bob Dole in V trials
05/11/98 5,262,500 113 3/4 110 111 270M Viagra Rxs
05/12/98 3,895,800 111 15/16 110 1/8 111 7/8
05/13/98 3,248,300 112 3/4 110 1/8 110 1/8
05/14/98 5,065,800 110 5/16 107 1/8 108
05/15/98 6,623,300 108 15/16 104 7/16 104 7/16 Peabody Valley
05/18/98 5,707,100 110 11/16 105 110 1/2 300M Viagra RXs
05/19/98 7,552,000 113 11/16 111 9/16 112 13/16
05/20/98 3,474,200 114 3/16 112 1/8 112 13/16 Peabody Peak
05/21/98 6,291,800 112 13/16 108 1/16 109 1/8 Viagra/Nitro warning
05/22/98 9,702,600 109 7/8 104 105 7/16 6 deaths reported
05/25/98 Memorial Day
05/26/98 6,303,800 106 15/16 103 1/16 103 3/16
05/27/98 6,692,200 108 101 3/8 108 ML Maintains Buy
05/28/98 4,064,500 107 5/8 105 5/8 106 3/8 PFE supports Viagra label
05/29/98 3,741,100 107 15/16 104 1/2 104 13/16 ICOS in news
06/01/98 4,251,100 104 7/8 100 3/8 103 15/16 Peabody Valley
06/02/98 3,138,200 105 7/8 102 1/2 103 3/8 AUA Meeting
06/03/98 2,625,500 104 15/16 102 13/16 103 AUA Meeting
06/04/98 3,698,400 107 5/8 102 3/16 107 AUA Meeting
06/05/98 4,231,500 108 3/4 106 108 3/8
06/08/98 2,809,200 109 13/16 107 1/2 108 7/16
06/09/98 6,319,400 112 7/8 107 3/4 112 1/2 FDA V Release
06/10/98 4,856,200 111 1/8 107 1/16 109 WSJ Drug Interactions
06/11/98 3,273,300 110 3/8 107 107
06/12/98 3,399,500 109 1/2 106 5/8 109 3/8
06/15/98 3,134,700 109 1/4 106 7/8 108 3/8 Dow- 200
06/16/98 3,376,700 110 3/8 108 1/8 109 11/16 Schneider sold
06/17/98 4,463,200 112 11/16 110 1/2 112 1/16
06/18/98 4,147,600 114 15/16 112 3/16 114 1/4 Peabody Peak
06/19/98 5,484,900 114 15/16 109 13/16 111 1/4 Zeldox non-approval
06/22/98 3,177,200 112 3/4 109 13/16 111 7/16
06/23/98 3,961,200 111 15/16 109 1/4 110 3/16
06/24/98 3,736,800 110 3/8 108 3/4 110 1/8
06/25/98 2,878,000 112 1/2 110 1/2 110 13/16
06/26/98 2,635,800 112 5/8 110 5/8 111 15/16
06/29/98 5,244,400 111 1/2 108 1/4 109 15/16
06/30/98 5,190,200 108 3/4 106 5/8 108 1/2 DLJ Switch to WLA
07/01/98 3,857,700 109 15/16 106 5/16 107 3/16 -7.5% off Peak
07/02/98 2,740,300 109 1/2 106 9/16 107 1/2 Public Citizen/HMOs
07/03/98 Independence Day Barrons: V to Fade?
07/06/98 4,746,500 109 1/2 105 5/8 109 7/16 Peabody Valley
07/07/98 3,661,200 111 9/16 109 9/16 111 IMS: V to $1 Billion
07/08/98 3,920,100 114 3/16 111 1/8 113 1/2
07/09/98 4,338,600 115 5/8 112 3/4 115 5/8 EPS: $0.47 (+$.03)
07/10/98 8,446,800 118 1/8 113 118
07/13/98 5,540,600 120 5/8 117 15/16 118 11/16
07/14/98 4,130,500 120 9/16 118 1/16 118 9/16 Peabody Peak
07/15/98 3,541,400 118 9/16 115 13/16 116 House panel V action
07/16/98 3,199,300 117 7/8 115 3/16 117 13/16
07/17/98 3,128,700 117 1/4 115 5/8 115 5/8 Viagra lawsuit
07/20/98 2,964,100 118 1/2 115 9/16 117 15/16 V Rxs -13.8%
07/21/98 3,706,300 117 7/8 114 1/16 114 1/8 MRK misses EPS
07/22/98 4,538,100 116 3/4 111 3/8 116 3/8
07/23/98 4,107,100 115 1/2 111 111 5/8 Dow -196
07/24/98 4,877,700 114 3/4 112 113 1/2 Upbeat analysts' meeting
07/27/98 3,643,900 114 13/16 111 5/8 114 V Rxs +5.8%
07/28/98 3,365,500 114 111 111 5/8
07/29/98 3,704,700 112 3/4 109 1/8 109 1/8 Valley strike price reached
07/30/98 2,714,700 112 3/8 109 7/8 112 Dow +112
07/31/98 2,776,900 112 5/8 108 9/16 110 1/16
08/03/98 2,637,600 111 1/8 108 5/8 109 11/16 V Rxs -6.0%
08/04/98 5,248,300 110 3/4 104 3/4 105 Dow -299
08/05/98 4,556,900 106 3/8 102 5/8 105 15/16
08/06/98 3,355,000 106 7/8 104 1/16 105 5/16
08/07/98 4,363,300 105 1/2 102 1/8 103 1/2
08/10/98 3,287,500 105 3/4 103 1/2 103 13/16 ACC/AHA V Report
08/11/98 5,898,100 104 5/16 98 1/2 103 15/16 Peabody Valley
08/12/98 3,858,800 104 15/16 101 1/4 101 15/16 WSJ -2 eye patients
08/13/98 3,614,500 104 101 1/2 102
08/14/98 2,680,800 103 1/4 101 1/16 101 3/16 Howmedica Sold
08/17/98 4,645,900 104 7/8 100 3/4 104 5/8 V Rxs +1%
08/18/98 4,349,900 107 9/16 103 7/16 107 1/2
08/19/98 3,343,200 108 15/16 106 3/8 108 15/16 Peabody Peak
08/20/98 3,194,400 108 13/16 105 1/2 105 3/4 Public Citizen V petition
08/21/98 3,887,200 106 1/4 102 1/16 105 7/8 Soros reports $.5B position
08/24/98 4,058,600 108 1/8 104 7/16 104 15/16 Celebra expedited review
08/25/98 5,241,900 108 5/8 106 106 1/2 EU V Approval
08/26/98 4,242,900 108 7/8 103 5/8 108 1/8 V associated w 69 deaths
08/27/98 4,053,100 107 3/4 103 1/2 103 13/16 Dow -358
08/28/98 4,821,800 104 7/8 100 3/8 101 5/8 Dow-114
08/31/98 8,156,300 102 1/16 93 93 Dow-512
09/01/98 10,640,800 99 92 96 1/2 Peabody Valley
09/02/98 6,494,600 101 5/8 98 3/8 100 1/16
09/03/98 4,944,000 102 1/16 98 99 13/16 NEJM V Letters
09/04/98 9,096,100 96 1/4 93 1/2 95 1/8 Morgan Stanley Downgrade
09/07/98 Labor Day
09/08/98 5,358,100 100 13/16 97 1/16 100 3/4 DJ: +381
09/09/98 4,725,000 101 9/16 98 98 3/16 DJ:-156
09/10/98 4,324,600 97 93 9/16 94 1/2 DJ:-249/Clinton
09/11/98 6,451,300 100 13/16 95 100 1/2 ML Supports Pharma
09/14/98 3,675,400 103 5/8 100 3/4 103 1/8 V Rxs +10%
09/15/98 2,603,500 103 7/8 101 1/2 102 9/16 EU V Approval
09/16/98 3,269,200 103 100 1/8 101 1/2 V Not On NHS
09/17/98 2,648,100 100 1/16 98 1/4 99 1/4
09/18/98 3,523,400 99 7/8 97 1/4 97 1/4 Lancet V Letter
09/21/98 2,869,900 99 1/8 95 97 5/8 Clinton Tapes
09/22/98 3,136,700 101 1/2 99 1/4 101 7/16
09/23/98 4,764,800 106 1/2 101 1/2 106 1/2 Dow +257
09/24/98 5,101,800 108 3/4 104 3/8 107 1/2 $5 B Stock Buyback
09/25/98 2,864,400 108 105 3/4 106 5/8
09/28/98 3,235,200 109 3/16 105 1/4 106 1/16 Peabody Peak
09/29/98 3,052,500 108 1/8 105 5/8 106 13/16 Fed reduces rates
09/30/98 3,627,600 108 1/16 105 5/8 105 15/16 DRIP day
10/01/98 3,853,400 104 11/16 99 3/8 99 5/8 Dow-210 LLY/ICOS
10/02/98 4,309,500 100 96 1/2 99 1/16
10/05/98 5,505,700 98 13/16 93 94 5/8 V Rxs -5%
10/06/98 7,462,200 96 11/16 88 1/8 89 3/8
10/07/98 6,766,000 92 15/16 88 3/4 90 5/8 JP Morgan recommends PFE
10/08/98 5,915,200 90 86 89 5/8 Peabody Valley
10/09/98 3,594,400 93 3/4 88 1/2 92 15/16 Dow +167
10/12/98 2,570,700 96 15/16 93 1/16 93 1/4 V Rxs +11%
10/13/98 2,567,700 96 3/8 93 1/4 95 1/2 EPS $0.51 -$0.6 from Zachs
10/14/98 11,810,800 97 1/8 88 1/2 96 3/8 Analysts Reiterate Buys
10/15/98 4,761,600 99 1/4 94 9/16 97 1/2 Dow +330, Fed reduces rates
10/16/98 3,977,600 98 15/16 96 9/16 98 3/16 Dow +117
10/19/98 3,424,500 99 13/16 97 1/16 97 9/16 Analysts Reiterate Buys
10/20/98 3,921,500 99 95 13/16 96 11/16 VRxs -1%
10/21/98 3,920,700 98 7/16 95 1/2 98
10/22/98 2,490,800 100 3/4 97 5/8 100 3/4
10/23/98 4,549,800 104 1/2 99 11/16 103 13/16
10/26/98 3,796,000 106 7/8 104 106 1/2 V Rxs -2%
10/27/98 3,278,400 106 7/8 105 7/8 106 5/16
10/28/98 2,459,100 106 3/4 104 5/8 105 11/16
10/29/98 2,600,200 107 3/4 105 3/16 107 5/8
10/30/98 2,742,300 108 1/4 106 5/8 107
11/02/98 3,003,700 108 1/2 106 1/4 108 1/2 V Rxs -3%
11/03/98 2,344,800 109 7/16 107 5/16 109 1/4 Election Day- Dems surprise
11/04/98 4,014,900 110 106 106
11/05/98 2,933,800 107 1/2 105 107 3/8
11/06/98 3,638,600 109 3/4 106 5/8 109 1/2 1998 R&D Meeting
11/09/98 2,728,400 109 11/16 107 108 1/4 V Rxs +2%
11/10/98 3,035,900 109 3/4 106 13/16 108 5/8 ACR Meeting
11/11/98 2,607,400 108 1/2 105 1/2 106 1/16 AHA Meeting
11/12/98 2,126,800 106 1/2 104 104 5/16
11/13/98 1,789,700 105 15/16 104 3/4 105 1/2
11/16/98 2,166,300 108 15/16 106 9/16 108 13/16 V Rxs +5%
11/17/98 3,553,000 111 108 109 1/2
11/18/98 2,749,800 111 5/8 108 9/16 111 3/8
11/19/98 3,245,200 111 3/4 110 1/16 110 9/16
11/20/98 2,412,800 112 110 3/8 112 Dow +104
11/23/98 4,944,800 116 7/8 112 5/16 116 11/16 Dow +215
11/24/98 3,464,100 116 7/8 113 1/2 114 Possible Peabody Peak
11/25/98 2,520,700 115 3/16 112 5/8 114 3/8 Change in V label
11/27/98 Thanksgiving
11/27/98 982,400 115 113 13/16 114
11/30/98 2,183,100 114 11/16 111 5/8 111 15/16 Dow -217
12/01/98 3,179,900 111 15/16 108 5/8 110 15/16 Possible Peabody Valley
12/02/98 2,743,400 113 1/2 110 7/16 113 1/16 Celebrex FDA panel
12/03/98 2,746,900 114 15/16 110 1/4 110 1/2 Dow -185
12/04/98 2,615,600 113 5/16 110 9/16 112 5/8
12/07/98 2,302,100 115 113 3/4 114 3/8 V refills very strong
12/08/98 2,797,700 116 3/16 114 1/2 116 3/16
12/09/98 3,186,000 117 9/16 115 1/16 116 1/8
12/10/98 2,874,900 117 3/16 113 3/4 114
12/11/98 2,082,800 115 113 1/8 114 7/8 Bob Dole hired
12/14/98 2,441,700 113 5/8 111 1/16 111 3/4 Dow -126
12/15/98 2,788,100 115 110 3/16 115
12/16/98 2,495,600 116 1/4 115 1/8 115 3/4 US bombs Iran
12/17/98 2,633,800 117 5/8 115 13/16 116 7/8 Pending Peabody Peak
12/18/98 3,118,600 116 3/4 115 1/2 116 Clinton Impeached
12/21/98 2,834,000 118 1/8 114 1/2 115 1/16 V approval in Japan
12/22/98 2,153,100 117 13/16 114 7/8 117 3/16
12/23/98 3,427,500 120 13/16 117 3/4 120 3/8
12/24/98 695,200 120 1/4 118 13/16 119 3/8
12/25/88 Christmas
12/28/98 1,729,300 120 7/16 118 1/2 119 7/16 V Rxs +5.1%
12/29/98 3,813,600 125 5/8 119 1/2 124 3/8 Forbes Company of Year
12/30/98 2,851,400 126 11/16 123 1/2 126 1/8
12/31/98 2,789,900 128 15/16 125 125 Celebrex Approved



To: JEB who wrote (6594)1/1/1999 11:05:00 AM
From: BigKNY3  Read Replies (1) | Respond to of 9523
 
Monsanto - FDA -2: Celebrex Not Considered New Drug Class
By Otesa Middleton

12/31/98
Dow Jones News Service

WASHINGTON (Dow Jones)--Monsanto Co.'s (MTC) Celebrex won approval from the U.S. Food and Drug Administration Thursday, making it the first Cox-2 inhibitor cleared by the agency.

The FDA approved the drug for rheumatoid arthritis and osteoarthritis.

The drug works by inhibiting the enzyme cyclooxygenase-2, called Cox-2, which causes inflammation.

The agency's release said Celebrex is a member of the NSAID, or non-steroidal anti-inflammatory drug class, which includes ibuprofen, aspirin and other popular pain killers.

One of the most common side effects of NSAIDs is gastrointestinal ulcers, which are believed to be caused because other NSAIDs block both Cox-1 and Cox-2.

Cox-1 is thought to protect the stomach lining. "It is therefore hoped that Celebrex will have safety advantages compared to other NSAID products," the FDA's release said.

When Monsanto applied for Celebrex's approval, the company asked the drug be considered the first in a new class of drugs that only work to inhibit Cox-2.

A federal panel had advised the agency that the drug should still be considered an NSAID