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Biotech / Medical : Cistron Biotechnology(CIST)$.30 -- Ignore unavailable to you. Want to Upgrade?

To: Walter Morton who wrote (1998)	3/7/1999 1:39:00 AM
From: Walter Morton	Read Replies (1) \| Respond to of 2742

Biologic basis for interleukin-1 in disease. Dinarello CA. Blood. 1996;87:2095-2147. Interleukin-1 (IL-1a and IL-1b) is the prototypic "multifunctional" cytokine. Unlike the lymphocyte and colony-stimulating growth factors, IL-1 affects nearly every cell type and often in concert with other cytokines or small mediator molecules. Although some lymphocyte and colony-stimulating growth factors may be therapeutically useful, IL-1 is a high inflammatory cytokine, and the margin between clinical benefit and unacceptable toxicity in humans is narrow.