Hybridon HYBN, for discussion of antisense drugs.

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Biotech / Medical
Hybridon HYBN, for discussion of antisense drugs.

An SI Board Since December 1996

Posts	SubjectMarks	Bans
42	5	0

Emcee: John Zwiener	Type: Unmoderated

Introduction Compact

I came across this lead the-scientist.library.upenn.edu
when a friend asked me to check out hybn. It explains antisense
technology in basic and advanced terms so that anyone can get
something from the explaination. It is very intriging. But the clinical
trials are only at phase Ib-II at most and only a total of 5 drugs are
under evaluation. HYBN has 2 going, ISIS I think has some, GILD
has some and may have a drug approved,but I'm not sure it is an
antisense drug.

Very risky at this time when biotechs are not responding to promises,
but instead going up only on results that will result in drug sales in the
near term. This is not one of those. It will be at least a year or two
before we see if this tech lives up to it's promise.

Very elegant tech and relatively simple, but is only recently practical
due to technology advances and a critical mass of knowledge. I
was stunned things have gone this far. I often talk to others of the
promise of biotech, but I thought it was 5-10 years off.

Don't take me wrong, but this tech really could result in effective
treatments with no or low toxicity for cancer, any virus, any bacteria
or fungus. I won't elaborate more at this time, but if you read about it
you will wonder why you have not heard or at least understood this
before. I tried to read about it in an article about ISIS and I could not
rapidly figure it out. It turns out it was so easy that the author of that
other article must not be a good teacher, or maybe it's not that easy
to understand.

I would like to hear from those who have followed this for awhile.
If no one answers, I'll just start talking to myself in a couple of days.

PS- I also found an article that said a closed down mutual fund
had made unauthorized trades in the antisense companies and
warned that those stocks would drop as the fund liquidated their
holdings. The article was about a month old and sure enough, the
prices have been cratering. I'll try to find it and be more specific.

Go to reply# or date (mm/dd/yy):

Reply	Message Preview	From	Recs	Posted
42	over 600k vol here today on this one ...it's 10k looks dire, yet rumors of	2MAR$	-	6/20/2000
41	Monday could be very interesting... Stockprowler.com has discovered little Hybr	Arizona997	-	12/19/1999
40	Huge move today for HYBN, but the volume wasnt' that great. No news. Any	JMarcus	-	12/8/1999
39	You can find links to past press releases by running a search for HYBN on www.b	JMarcus	-	7/11/1999
38	Are their any other chat rooms for the stock? Do they have any drugs in the pi	priceguy	-	7/10/1999
37	I think antisense holds great promise, so this company ought to have a lot of i	JMarcus	-	7/10/1999
36	Noted good increase today and find tech story interesting. Are there any other	priceguy	-	7/9/1999
35	On Friday John Naples, Controller at HYBN, left me a very prompt and courteous	JMarcus	-	6/9/1999
34	Hi, Deepest apologies for the delay. I understand that a big share holder dump	Mounir Abouzakhm	-	6/8/1999
33	Any idea why the stock price is cratering? Stock is down 60% today. Marc	JMarcus	-	6/4/1999
32	A joke "The loss of E. Andrews Grinstead III's services could have a	Mounir Abouzakhm	-	5/21/1999
31	An Advisory Panel recommends approval of ISIP's antisense drug today and HY	JMarcus	-	7/22/1998
30	Marcus, In the Prohost's last issue they mentioned that they expect good n	Mounir Abouzakhm	-	2/18/1998
29	Since your posting HYBN has gradually traded its way back up to 2-7/8 (from a 5	JMarcus	-	2/17/1998
28	While we're naming all the stars in the anti-sense heavens, here is a very	mike head	-	2/8/1998
27	Thanks for the info, there is another one here in Montreal, Qc, Canada called M	Louis XIX	-	1/29/1998
26	The following article mentions two more antisense companies (both from Canada):	JMarcus	-	1/29/1998
25	Hi Marcus, Thank you very much for the post. That was very kind of you. What	Mounir Abouzakhm	-	1/26/1998
24	Thursday January 22, 3:56 pm Eastern Time Company Press Release SOURCE: Hybri	JMarcus	-	1/23/1998
23	Other antisense companies include Enzo Biochem (ENZ), AntiVirals (AVII), and Ge	JMarcus	-	1/22/1998
22	Dear Mounir, investing in biotech IPO is very risky, sorry for you	Louis XIX	-	1/22/1998
21	Dear Mounir - sorry to hear that. Well, the problem with tech, especially biote	Bosco	-	1/21/1998
20	Dear Bosco, Thanks for ansewring my post. I was hoping that another pharmacuet	Mounir Abouzakhm	-	1/21/1998
19	Dear Peter - if its private financing is what the many of us SI known as the fl	Bosco	-	1/21/1998
18	>>There is a likelihood that HYBN will join the rank of so many cos	Peter Church	-	1/21/1998

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