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Micromet Key facts: Business Design and development of novel antibody-based drugs Markets Cancer, Inflammation, Autoimmunity Drug Pipeline MT201, a fully human antibody for treatment of tumors, in phase II MT103, a BiTE™ molecule for treatment of B cell lymphomas and leukemias, in phase I MT110, a BiTE™ molecule for treatment of carcinomas, preclinical MT203, a human antibody for treatment of inflammatory diseases, preclinical D93 (humanized antibody), Solid Tumors, Pre-clinical Additional BiTE™s and human antibodies in drug discovery Technologies BiTE™ BiTE™s are a novel format of bispecific antibody derivatives. They are unique in their ability to activate the body’s killer T cells against target cells. This novel mode of action translates into outstanding potency and specificity in target cell elimination. SCA (single-chain antibodies) SCAs are small antibody fragments, which are cost-effective to produce and extremely versatile for protein engineering. They provide an ideal structural basis for the development of novel drug formats as exemplified by their use in BiTE™ drugs. Partners Serono, MedImmune, Enzon, Boehringer Ingelheim Status: Reverse merger with CNVX in Q2,2006 Proposed Ticker: MITI Foundation 1993 as spin-off from the Institute for Immunology, Munich University Pipeline micromet.de Most Interesting Research Paper: nature.com Reverse Merger Details and Future Goals: biz.yahoo.com micromet.de Thanks for your interest! | ||||||||||||||
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