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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?

To: Bluegreen who wrote (10046)5/17/1999 5:58:00 PM
From: John Patterson  Read Replies (3) | Respond to of 17367
 
Think of it this way BG, the antibiotics kill the bacteria, however as the bacteria die they release lps from their cell wall. This causes a HYPER activation of the complement cascade and all of its associated mediators. In other words a whole body inflammatory response, this is the real problem as this can progress to DIC (dissesimanated intravascular coagulopathy) where you have clotting on a micro level (at the capillary level) and bleeding on a macro level, (around the central lines, the gingiva etc). The micro clotting eventually results in a macro shut-down of various organs or mutil sytem failure (death).



To: Bluegreen who wrote (10046)5/18/1999 6:42:00 PM
From: Cacaito  Read Replies (2) | Respond to of 17367
 
Bluegreen, 30% to 40% of suspected septic shock patients are never positive for bacteria.

Many who were positive for bacteria become negative and shock keeps going on and death results.

This is a fact that plagues all sepsis studies and ESPECIALLY septic shock ones.

Forget Faith, Welcome FACT.


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